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NeoSome Life Sciences, LLC

NeoSome Life Sciences, LLC is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Antibodies

  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Immunodetection Use antibodies to identify a protein or antigen.

Bioimaging

  • Bioimaging Visualize biological process non-invasively in real time.
  • In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
  • In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
  • Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.

Biomarkers

  • Adipogenesis Assay Detect and quantify intracellular triglyceride accumulation in adipocytes.
  • Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Show all 7 in Biomarkers 1 more
  • Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Show all 76 services 64 more

Cell Culture and Characterization

  • Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
  • Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.

Chemical and Compound Analysis

  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.

Chemistry, Manufacturing and Controls (CMC)

  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Disease Models

  • Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
  • Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
  • Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
  • Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Show all 9 in Disease Models 3 more
  • LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
  • Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
  • Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.

General in vivo Toxicology

  • Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
  • Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
  • Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
  • Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
  • Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
Show all 8 in General in vivo Toxicology 2 more
  • Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
  • Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.

In Vitro Assays

  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Microbiology Study microbes and their role in human health.
  • Serine Protease Assay Detect apoptosis by measuring protease activity.

In Vitro Pharmacology

  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation

In Vivo ADME

  • Chronic Bile Duct Cannulation (BDC) Study - Dog / Canine Conduct a bile duct cannulation (BDC) study in dogs/canines to support the absorption, distribution, metabolism and excretion profiling of your compound.
  • Chronic Bile Duct Cannulation (BDC) Study - Rat Conduct a bile duct cannulation (BDC) study in rats to support the absorption, distribution, metabolism and excretion profiling of your compound.
  • Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

In Vivo Pharmacokinetics

  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
  • In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
  • Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
  • Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
  • Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Show all 9 in In Vivo Pharmacokinetics 3 more
  • Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
  • Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
  • Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Model Development

  • Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
  • Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
  • PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
  • SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
  • SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
Show all 9 in Model Development 3 more
  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
  • Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Oncology Models

  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
  • Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
  • Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Pharmacology

  • In Vivo Pharmacology Study the effects of drug candidates in animal models

Product Orders

  • Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
  • Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Other services

  • In Vivo Hollow Fiber Assay Evaluate test items concurrently with three different tumor cell lines within the same mouse.
  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Billerica 1 site

Source: Scientist.com supplier network (site locations)

Supplier diversity

SAM.gov small-business designations

Minority-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

Source: U.S. federal System for Award Management (SAM.gov), self-certified by the supplier

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Sources: Scientist.com supplier network, U.S. federal System for Award Management (SAM.gov).

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