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Clinical trial

A Phase I Study of ABT-888, an Oral Inhibitor of Poly (ADP-Ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

NCT00946335 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Study of ABT-888, an Oral Inhibitor of Poly (ADP-Ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Completed
Start date
July 31, 2009
Completion date
June 30, 2014
Enrollment
31 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

childhood atypical teratoid/rhabdoid tumor, childhood central nervous system germ cell tumor, childhood choroid plexus tumor, childhood craniopharyngioma, childhood ependymoblastoma, childhood grade i meningioma, childhood grade ii meningioma, childhood grade iii meningioma, childhood high-grade cerebellar astrocytoma, childhood high-grade cerebral astrocytoma, childhood infratentorial ependymoma, childhood low-grade cerebellar astrocytoma, childhood low-grade cerebral astrocytoma, childhood medulloepithelioma, childhood mixed glioma, childhood oligodendroglioma, childhood supratentorial ependymoma, recurrent childhood brain stem glioma, recurrent childhood brain tumor, recurrent childhood cerebellar astrocytoma, recurrent childhood cerebral astrocytoma, recurrent childhood ependymoma, recurrent childhood medulloblastoma, recurrent childhood pineoblastoma, recurrent childhood spinal cord neoplasm, recurrent childhood subependymal giant cell astrocytoma, recurrent childhood supratentorial primitive neuroectodermal tumor, recurrent childhood visual pathway and hypothalamic glioma