Clinical trial
A Phase I, Open-label, Multicentre, Dose Escalation Study to Assess the Safety and Tolerability, and Pharmacokinetics of AZD1480 in Asian Patients With Advanced Solid Malignancies and Asian Patients With Child-Pugh A to B7 Advanced Hepatocellular Carcinoma (HCC) in the Escalation Phase, Estimated Glomerular Filtration Rate(EGFR) or ROS Mutant NSCLC and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour With Biopsy Available in the Expansion Phase.
NCT01219543 is registered in ClinicalTrials.gov with AstraZeneca as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase I, Open-label, Multicentre, Dose Escalation Study to Assess the Safety and Tolerability, and Pharmacokinetics of AZD1480 in Asian Patients With Advanced Solid Malignancies and Asian Patients With Child-Pugh A to B7 Advanced Hepatocellular Carcinoma (HCC) in the Escalation Phase, Estimated Glomerular Filtration Rate(EGFR) or ROS Mutant NSCLC and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour With Biopsy Available in the Expansion Phase.
- Lead sponsor
- AstraZeneca
- Phase
- Phase 1
- Overall status
- Terminated
- Start date
- November 30, 2010
- Completion date
- December 31, 2012
- Enrollment
- 47 (actual)
- Sites
- 1
Conditions
As the registry lists them; a condition with its own page is linked.
advanced solid malignancies, child-pugh a to b7 advanced hepatocellular carcinoma, egfr and/or ros mutant nsclc, gastric cancer, lung metastasis carcinoma, solid tumour