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Clinical trial

A Phase 1 Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination With Ipilimumab (CaboNivoIpi) in Patients With Advanced/Metastatic Urothelial Carcinoma and Other Genitourinary Tumors

NCT02496208 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT02496208
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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination With Ipilimumab (CaboNivoIpi) in Patients With Advanced/Metastatic Urothelial Carcinoma and Other Genitourinary Tumors
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Active, not recruiting
Start date
July 22, 2015
Completion date
September 30, 2026
Enrollment
152 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

bladder small cell neuroendocrine carcinoma, bladder squamous cell carcinoma, bladder urothelial carcinoma, clear cell renal cell carcinoma, invasive bladder plasmacytoid urothelial carcinoma, invasive bladder sarcomatoid urothelial carcinoma, invasive sarcomatoid urothelial carcinoma, kidney medullary carcinoma, malignant genitourinary system neoplasm, malignant solid neoplasm, penile carcinoma, penile squamous cell carcinoma, renal cell carcinoma, renal pelvis urothelial carcinoma, sarcomatoid renal cell carcinoma, stage iii bladder cancer ajcc v8, stage iii penile cancer ajcc v8, stage iii renal cell cancer ajcc v8, stage iii renal pelvis and ureter cancer ajcc v8, stage iii renal pelvis cancer ajcc v8, stage iii ureter cancer ajcc v8, stage iii urethral cancer ajcc v8, stage iv bladder cancer ajcc v8, stage iv penile cancer ajcc v8, stage iv renal cell cancer ajcc v8, stage iv renal pelvis and ureter cancer ajcc v8, stage iv ureter cancer ajcc v8, stage iv urethral cancer ajcc v8, ureter urothelial carcinoma, urethral urothelial carcinoma