Clinical trial
A Phase 1b/2, Open-Label, Multicentre Study Assessing the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of MEDI4736 in Combination With AZD9150 or AZD5069 in Patients With Advanced Solid Malignancies and Subsequently Comparing AZD9150 and AZD5069 Both as Monotherapy and in Combination With MEDI4736 as Second Line Treatment in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck.
NCT02499328 is registered in ClinicalTrials.gov with AstraZeneca as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase 1b/2, Open-Label, Multicentre Study Assessing the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of MEDI4736 in Combination With AZD9150 or AZD5069 in Patients With Advanced Solid Malignancies and Subsequently Comparing AZD9150 and AZD5069 Both as Monotherapy and in Combination With MEDI4736 as Second Line Treatment in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck.
- Lead sponsor
- AstraZeneca
- Phase
- Phase 1/2
- Overall status
- Completed
- Start date
- August 6, 2015
- Completion date
- October 8, 2025
- Enrollment
- 340 (actual)
- Sites
- 44
Conditions
As the registry lists them; a condition with its own page is linked.
advanced solid tumors & metastatic squamous cell carcinoma of the head and neck