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Clinical trial

A Phase Ib Trial Evaluating the Safety of Copanlisib, Letrozole, and Palbociclib in Metastatic Breast Cancer and Phase II Trial Comparing the Molecular Effects of Neoadjuvant Copanlisib in Combination With Palbociclib and Letrozole, vs. Copanlisib With Letrozole, vs. Palbociclib With Letrozole for Patients With Hormone Receptor Positive, HER2 Normal Breast Cancer

NCT03128619 is registered in ClinicalTrials.gov with Jonsson Comprehensive Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase Ib Trial Evaluating the Safety of Copanlisib, Letrozole, and Palbociclib in Metastatic Breast Cancer and Phase II Trial Comparing the Molecular Effects of Neoadjuvant Copanlisib in Combination With Palbociclib and Letrozole, vs. Copanlisib With Letrozole, vs. Palbociclib With Letrozole for Patients With Hormone Receptor Positive, HER2 Normal Breast Cancer
Lead sponsor
Jonsson Comprehensive Cancer Center
Phase
Phase 1
Overall status
Terminated
Start date
August 2, 2017
Completion date
March 31, 2022
Enrollment
10 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

estrogen receptor positive, her2/neu negative, invasive breast carcinoma, multifocal breast carcinoma, postmenopausal, progesterone receptor positive, stage i breast cancer, stage ia breast cancer, stage ib breast cancer, stage ii breast cancer, stage iia breast cancer, stage iib breast cancer, stage iii breast cancer, stage iiia breast cancer, stage iiib breast cancer, stage iiic breast cancer, stage iv breast cancer