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Clinical trial

Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects With Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma

NCT03389802 is registered in ClinicalTrials.gov with Pediatric Brain Tumor Consortium as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects With Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma
Lead sponsor
Pediatric Brain Tumor Consortium
Phase
Phase 1
Overall status
Completed
Start date
March 1, 2018
Completion date
July 20, 2026
Enrollment
32 (actual)
Sites
11

Conditions

As the registry lists them; a condition with its own page is linked.

cns primary tumor, not otherwise specified (nos), diffuse intrinsic pontine gliomas (dipg), ependymoma, not otherwise specified (nos), glioblastoma multiforme, high-grade astrocytoma not otherwise specified (nos), medulloblastoma