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Clinical trial

Phase I Multi-Center Study of Hypofractionated Radiotherapy in Combination With Durvalumab and Tremelimumab in Patients With Recurrent/Metastatic Advanced Cervical, Vaginal, or Vulvar Cancer

NCT03452332 is registered in ClinicalTrials.gov with M.D. Anderson Cancer Center as lead sponsor.

NCT NCT03452332
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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Multi-Center Study of Hypofractionated Radiotherapy in Combination With Durvalumab and Tremelimumab in Patients With Recurrent/Metastatic Advanced Cervical, Vaginal, or Vulvar Cancer
Lead sponsor
M.D. Anderson Cancer Center
Phase
Phase 1
Overall status
Completed
Start date
July 18, 2018
Completion date
August 11, 2023
Enrollment
20 (actual)
Sites
2

Conditions

As the registry lists them; a condition with its own page is linked.

advanced cervical adenocarcinoma, advanced vaginal carcinoma, advanced vulvar carcinoma, human papillomavirus-related cervical squamous cell carcinoma, human papillomavirus-related vulvar squamous cell carcinoma, metastatic cervical adenocarcinoma, metastatic cervical carcinoma, metastatic cervical squamous cell carcinoma, not otherwise specified, metastatic vaginal adenocarcinoma, metastatic vaginal carcinoma, metastatic vulvar carcinoma, recurrent cervical adenocarcinoma, recurrent cervical carcinoma, recurrent cervical squamous cell carcinoma, not otherwise specified, recurrent vaginal carcinoma, recurrent vulvar carcinoma, stage iii cervical cancer ajcc v8, stage iii vaginal cancer ajcc v8, stage iii vulvar cancer ajcc v8, stage iiia cervical cancer ajcc v8, stage iiia vulvar cancer ajcc v8, stage iiib cervical cancer ajcc v8, stage iiib vulvar cancer ajcc v8, stage iiic vulvar cancer ajcc v8, stage iv cervical cancer ajcc v8, stage iv vaginal cancer ajcc v8, stage iv vulvar cancer ajcc v8, stage iva cervical cancer ajcc v8, stage iva vaginal cancer ajcc v8, stage iva vulvar cancer ajcc v8, stage ivb cervical cancer ajcc v8, stage ivb vaginal cancer ajcc v8, stage ivb vulvar cancer ajcc v8, vaginal squamous cell carcinoma, not otherwise specified, vulvar adenocarcinoma, vulvar squamous cell carcinoma