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Clinical trial

Phase Ib, Open Label, Combination Study of Nintedanib With 5-Azacitidine in Acute Myeloid Leukemia Characterized by HOX Gene Overexpression, That Are Not Candidates of Intensive Chemotherapy

NCT03513484 is registered in ClinicalTrials.gov with Northwestern University as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase Ib, Open Label, Combination Study of Nintedanib With 5-Azacitidine in Acute Myeloid Leukemia Characterized by HOX Gene Overexpression, That Are Not Candidates of Intensive Chemotherapy
Lead sponsor
Northwestern University
Phase
Phase 1
Overall status
Active, not recruiting
Start date
November 14, 2018
Completion date
January 31, 2027
Enrollment
44 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

acute myeloid leukemia with t(9;11)(p22.3;q23.3); mllt3-kmt2a, fibroblast growth factor basic form measurement, flt3 internal tandem duplication, recurrent adult acute myeloid leukemia, refractory acute myeloid leukemia