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Clinical trial

Phase 1 Dose Escalation Study of CPX-351 for Patients With Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia After Failure to Hypomethylating Agents

NCT03896269 is registered in ClinicalTrials.gov with M.D. Anderson Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1 Dose Escalation Study of CPX-351 for Patients With Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia After Failure to Hypomethylating Agents
Lead sponsor
M.D. Anderson Cancer Center
Phase
Phase 1
Overall status
Recruiting
Start date
May 14, 2019
Completion date
December 31, 2027
Enrollment
38 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

blasts 10-19 percent of bone marrow nucleated cells, blasts more than 5 percent of bone marrow nucleated cells, high risk chronic myelomonocytic leukemia, recurrent chronic myelomonocytic leukemia, recurrent high risk myelodysplastic syndrome, refractory chronic myelomonocytic leukemia, refractory high risk myelodysplastic syndrome