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Clinical trial

A Phase 1b Study of Menin Inhibitor SNDX-5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

NCT05886049 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1b Study of Menin Inhibitor SNDX-5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Recruiting
Start date
June 20, 2024
Completion date
December 31, 2027
Enrollment
38 (estimated)
Sites
23

Conditions

As the registry lists them; a condition with its own page is linked.

acute myeloid leukemia, acute myeloid leukemia with kmt2a rearrangement, acute myeloid leukemia with npm1 mutation, secondary acute myeloid leukemia