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Clinical trial

A Randomized, Controlled, Multi-centers, Non Inferiority Phase II Clinical Study Comparing Iparomlimab and Tuvonralimab With Standard Chemotherapy Combined With PD-1/PD-L1 Monoclonal Antibody as First-line Treatment for MSI-H/dMMR Recurrent/Metastatic Gastric Cancer

NCT07127822 is registered in ClinicalTrials.gov with Peking University as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized, Controlled, Multi-centers, Non Inferiority Phase II Clinical Study Comparing Iparomlimab and Tuvonralimab With Standard Chemotherapy Combined With PD-1/PD-L1 Monoclonal Antibody as First-line Treatment for MSI-H/dMMR Recurrent/Metastatic Gastric Cancer
Lead sponsor
Peking University
Phase
Phase 2
Overall status
Recruiting
Start date
December 15, 2025
Completion date
December 31, 2028
Enrollment
106 (estimated)
Sites
10

Conditions

As the registry lists them; a condition with its own page is linked.

gastric / gastroesophageal junction adenocarcinoma, msi-h cancer