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Clinical trial

An Open-Label, Dose-Escalation Phase I Clinical Study of T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

NCT07474168 is registered in ClinicalTrials.gov with Zhejiang University as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
An Open-Label, Dose-Escalation Phase I Clinical Study of T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor
Lead sponsor
Zhejiang University
Phase
Phase 1
Overall status
Active, not recruiting
Start date
December 15, 2025
Completion date
February 29, 2032
Enrollment
9 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

tumor