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Clinical trial

Efficacy and Safety of Neoadjuvant Short-Course/Long-Course Radiotherapy Combined With Anti-PD-1/CTLA-4 Dual Immunotherapy for Locally Advanced Rectal Cancer: A Prospective, Randomized Controlled Trial (RADICAL Trial)

NCT07596290 is registered in ClinicalTrials.gov with Beijing Friendship Hospital as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Efficacy and Safety of Neoadjuvant Short-Course/Long-Course Radiotherapy Combined With Anti-PD-1/CTLA-4 Dual Immunotherapy for Locally Advanced Rectal Cancer: A Prospective, Randomized Controlled Trial (RADICAL Trial)
Lead sponsor
Beijing Friendship Hospital
Phase
Phase 2/3
Overall status
Not yet recruiting
Start date
July 15, 2026
Completion date
December 31, 2030
Enrollment
342 (estimated)
Sites
Not reported

Conditions

As the registry lists them; a condition with its own page is linked.

locally advanced rectal adenocarcinoma, neoadjuvant chemoradiation, neoadjuvant immunotherapy