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Clinical trial

AN INTERVENTIONAL, DOUBLE-BLIND, PLACEBO CONTROLLED, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF ATIRMOCICLIB (PF-07220060) PLUS GIREDESTRANT COMPARED TO GIREDESTRANT MONOTHERAPY AS ADJUVANT TREATMENT IN ADULT PARTICIPANTS WITH ESTROGEN RECEPTOR (ER)-POSITIVE, HER2-NEGATIVE EARLY-STAGE BREAST CANCER WITH MEDIUM OR HIGH RISK OF RECURRENCE (FOURLIGHT-4)

NCT07890597 is registered in ClinicalTrials.gov with Pfizer as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
AN INTERVENTIONAL, DOUBLE-BLIND, PLACEBO CONTROLLED, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF ATIRMOCICLIB (PF-07220060) PLUS GIREDESTRANT COMPARED TO GIREDESTRANT MONOTHERAPY AS ADJUVANT TREATMENT IN ADULT PARTICIPANTS WITH ESTROGEN RECEPTOR (ER)-POSITIVE, HER2-NEGATIVE EARLY-STAGE BREAST CANCER WITH MEDIUM OR HIGH RISK OF RECURRENCE (FOURLIGHT-4)
Lead sponsor
Pfizer
Phase
Phase 3
Overall status
Not yet recruiting
Start date
December 1, 2026
Completion date
August 20, 2042
Enrollment
3,800 (estimated)
Sites
Not reported

Conditions

As the registry lists them; a condition with its own page is linked.

early breast cancer, estrogen receptor positive (er+), human epidermal growth factor receptor 2 negative (her2-)

Lead sponsor's other trials

Pfizer, most recent start first.

Similar trials

Same condition (Breast Neoplasms) and phase, most recent start first.