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Clinical trial

A Phase I Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Clinical Activity of RO7836748 as Monotherapy and in Combination With Other Anti-Cancer Therapies in Participants With Advanced Solid Tumors With a RAS G12V Mutation

NCT07905924 is registered in ClinicalTrials.gov with Hoffmann-La Roche as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Clinical Activity of RO7836748 as Monotherapy and in Combination With Other Anti-Cancer Therapies in Participants With Advanced Solid Tumors With a RAS G12V Mutation
Lead sponsor
Hoffmann-La Roche
Phase
Phase 1
Overall status
Not yet recruiting
Start date
December 31, 2026
Completion date
March 30, 2032
Enrollment
540 (estimated)
Sites
Not reported

Conditions

As the registry lists them; a condition with its own page is linked.

solid tumors

Lead sponsor's other trials

Hoffmann-La Roche, most recent start first.