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Organization (Industry)

CytomX Therapeutics, Inc.

ClinicalTrials.gov lists CytomX Therapeutics, Inc. as lead sponsor of 10 trials. It has 29 active development programs and 4 approved assets.

US Industry Manufacturer CIK 0001501989

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2 0 2017 2026

Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.

2026 is partial: 1 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through October, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 0.6 trial starts a year over the five years to October, under the 5 a year the method needs.

This page covers CytomX Therapeutics, Inc.: 10 lead-sponsored trials and 3 legal-entity registrations.

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Disease areas (15)

Shown in this order: most trials first.

Disease areas
Disease area Trials
Breast Neoplasms 2
Carcinoma, Non-Small-Cell Lung 2
Head and Neck Neoplasms 2
Lung Neoplasms 2
Lymphoma 2

Trials by start year as sponsor or collaborator (7)

Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Show the table of trials by start year as sponsor or collaborator
Trials by start year as sponsor or collaborator
Year Trials started
2026 (partial year) 1
2024 2
2022 1
2020 2
2019 1
2018 1
2017 2

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

Active development programs (29)

Shown in this order: max phase, then active trials.

Active development programs
Drug Disease area Max phase Trials Ownership basis
CX-2009 Breast Neoplasms Phase 2 2 Experimental arm
IPILIMUMAB Melanoma Phase 2 1 Crowded, not lead
IPILIMUMAB Recurrence Phase 2 1 Crowded, not lead
CX-2009 Triple Negative Breast Neoplasms Phase 2 1 Experimental arm
CX-072 Breast Neoplasms Phase 2 1 Experimental arm

Approved assets (4)

Shown in this order: max phase first.

Approved assets
Drug Trials Ownership basis
IPILIMUMAB 2 Crowded, not lead
BEVACIZUMAB 2 Generic, not holder
Vemurafenib 1 Crowded, not lead
PEMBROLIZUMAB 1 Crowded, not lead

Sponsor delivery record (1)

Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.

Sponsor delivery record
Enrollment Timeline
0% hit target (n=7) 33% on time (n=6)

Journals published in (2)

Shown in this order: most published in first.

Journals published in
Journal Publications
Journal for immunotherapy of cancer 2
Clinical cancer research : an official journal of the American Association for Cancer Research 1

US granted patents (1)

Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.

US granted patents
US patents granted Granted in the last 5 years Most recent grant
87 32 2025-12-23

SEC-reported annual financials (11)

Shown in this order: newest fiscal year first; SEC EDGAR XBRL companyfacts; non-USD filers converted to USD at the annual average rate.

SEC-reported annual financials
Fiscal year Revenue Net income R&D
2025 $76.2M -$17.4M $68.7M
2024 $138M $31.9M $83.4M
2023 $101M -$569K $77.7M
2022 $53.2M -$99.3M $112M
2021 $37.3M -$116M $114M
2020 $100M -$32.9M $113M
2019 $57.5M -$102M $132M
2018 $59.5M -$84.6M $104M
2017 $71.6M -$43.1M $92.3M
2016 $12.8M -$58.9M $54.8M

Cash runway about 23 months at the end of FY2025. Estimate, derived not reported: $137M of cash and investments over $72.6M a year of net cash used in operations, averaged over the 3 reported fiscal years to FY2025.

Financing and grant events (23)

Shown in this order: most recent first; amounts in US dollars.

Financing and grant events
Date Round type Amount Source
2026-05-29 Royalty / licensing $37 SEC extracted
2026-03-19 Public offering $234M SEC extracted
2026-03-18 Follow-on offering $287M Registered offering ceiling EDGAR offerings
2026-03-16 Follow-on offering not disclosed EDGAR offerings
2026-03-16 Other financing not disclosed EDGAR offerings

Climate targets, as filed (1)

Climate targets, as filed
Reporting year Net-zero target
2025 not disclosed

Workforce and board diversity, as filed (1)

Workforce and board diversity, as filed
Reporting year Workforce % women Board % women
2025 not disclosed not disclosed

Latest dated events (120)

Shown in this order: newest first.

Latest dated events
Date Event Source
2026-12 Planned start Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-05-29 Royalty / licensing Funding rounds and grants (NIH RePORTER + SEC EDGAR)
2026-03-19 Public offering Funding rounds and grants (NIH RePORTER + SEC EDGAR)
2026-03-18 Follow-on offering Funding rounds and grants (NIH RePORTER + SEC EDGAR)
2026-03-16 Follow-on offering Funding rounds and grants (NIH RePORTER + SEC EDGAR)

Biomarker capability evidence (7)

Shown in this order: tier desc, then gene symbol.

Biomarker capability evidence
Gene Role Evidence
CD274 Trial sponsor Named in trial inclusion criteria
ERBB2 Trial sponsor Named in trial inclusion criteria
PDCD1 Trial sponsor Named in trial exclusion criteria
CD274 Trial sponsor Mentioned in trial text
ERBB2 Trial sponsor Mentioned in trial text

Not on this page

Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, organization relationships, clia clinical laboratory certificates, and biomarkers this organization publishes on.