Organization (Hospital)
Children's Hospital of Orange County
ClinicalTrials.gov lists Children's Hospital of Orange County as lead sponsor of 18 trials. It has 11 active development programs and 6 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 2 registered with a 2026 start date. The dashed outline is the pace from the 2 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 4.2 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers Children's Hospital of Orange County: 18 lead-sponsored trials and 1 legal-entity registration.
Disease areas (61)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Epilepsy | 5 |
| Pain | 3 |
| Seizures | 3 |
| Anemia | 2 |
| Brain Concussion | 2 |
Showing 5 of 61 disease areas.
Trials by start year as sponsor or collaborator (17)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 7 |
| 2024 | 2 |
| 2023 | 6 |
| 2022 | 3 |
| 2021 | 4 |
| 2020 | 4 |
| 2019 | 3 |
| 2018 | 1 |
| 2017 | 3 |
Showing 10 of 17 years.
Prediction, not a registry value: median of 35 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; 3 of 7 predicted trials reach the 36-month horizon. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (11)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| KZ101 | Autism Spectrum Disorder | Phase 2 | 1 |
| Fenfluramine | Spasms, Infantile | Phase 2 | 1 |
| Fenfluramine | Epilepsy | Phase 2 | 1 |
| +/- Bupivacaine HCl | Anterior Cruciate Ligament Injuries | Phase 1 | 1 |
| +/- Bupivacaine HCl | Anxiety Disorders | Phase 1 | 1 |
Showing 5 of 11 active programs.
Approved assets (6)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application) | 1 |
| Ferrous Fumarate | 1 |
| Ferric Carboxymaltose | 1 |
| Fenfluramine | 1 |
| +/- Bupivacaine HCl | 1 |
Showing 5 of 6 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 1 of 2 hit target (n=2) | 0 of 1 on time (n=1) |
Journals published in (95)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| The Journal of pediatrics | 5 |
| Brain injury | 3 |
| JAMA | 3 |
| Journal of pediatric orthopedics | 3 |
| The New England journal of medicine | 3 |
Showing 5 of 95 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 5 | 0 | 2021-09-21 |
Financing and grant events (7)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-07-23 | NIH grant | 706,005 | Reporter |
| 2025-07-15 | NIH grant | 852,280 | Reporter |
| 2025-02-18 | NIH grant | 546,164 | Reporter |
| 2024-02-29 | NIH grant | 613,028 | Reporter |
| 2024-02-15 | NIH grant | 255,000 | Reporter |
Showing 5 of 7 events.
FDA inspection record (1)
| Latest classification | Inspections |
|---|---|
| VAI | 8 |
Organization relationships (53)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| University of California System | Co sponsors trial with | 5 |
| Lurie Children's Hospital | Co sponsors trial with | 3 |
| Corewell Health | Co sponsors trial with | 2 |
| Wake Forest University | Co sponsors trial with | 2 |
| The University of Texas System | Co sponsors trial with | 2 |
Showing 5 of 53 relationships.
Latest dated events (66)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-04-29 | FDA inspection | FDA enforcement (warning and untitled letters, recalls, inspections, import refusals, debarment) |
| 2026-01-31 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-01-08 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-11-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-09-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 66 events.
CLIA clinical laboratory certificates (3)
Shown in this order: active first, then certificate type.
| Lab | Certificate | Status |
|---|---|---|
| CHILDREN'S HOSPITAL OF ORANGE COUNTY | Certificate of waiver | Active |
| CHILDREN'S HOSPITAL OF ORANGE COUNTY | Certificate of waiver | Active |
| CHILDREN'S HOSPITAL OF ORANGE COUNTY | Certificate of waiver | Terminated |
Biomarker capability evidence (32)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ACD | Trial sponsor | Named in trial inclusion criteria |
| ALK | Trial collaborator | Named in trial inclusion criteria |
| DMD | Trial collaborator | Named in trial inclusion criteria |
| FAP | Trial sponsor | Named in trial inclusion criteria |
| MSLNL | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 32 evidence rows.
Biomarkers this organization publishes on (156)
Shown in this order: most publications first.
Showing 5 of 156 biomarkers.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, sec-reported annual financials, fda warning letters, fda untitled letters, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, and workforce and board diversity, as filed.