Condition (MeSH)
Lacerations
ClinicalTrials.gov lists 139 trials for Lacerations or a narrower condition beneath it.
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Trials per phase (log scale)
1 more section with rows
139 of the 139 trials are tagged with Lacerations itself; the rest are tagged with a narrower condition beneath it.
When did Lacerations trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
- Other (Unknown)
Top of scale: 13
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 12 |
| 2025 | 10 |
| 2024 | 11 |
| 2023 | 9 |
| 2022 | 13 |
| 2021 | 9 |
| 2020 | 5 |
| 2018 | 9 |
| 2017 | 11 |
| 2016 | 4 |
Showing 10 of 22 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 14 trials starting in 2026 and about 12 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 30 months from start to primary completion across 11 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 80 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Lacerations trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 11 |
| Phase 2/3 | 1 |
| Phase 3 | 3 |
| Phase 4 | 12 |
| Not applicable | 76 |
| Observational | 31 |
| Unknown | 1 |
How many Lacerations trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 13 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 4 |
| Completed | 62 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Lacerations trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Aesculap AG | 2 |
| Instituto Nacional de Rehabilitacion | 2 |
| Alcon Research | 1 |
Which drugs are being tested for Lacerations? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Nitrous Oxide | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Control (placebo) group | 3 |
| Low Level Laser Therapy | 2 |
| Intranasal Ketamine | 2 |
| D. Midazolam | 2 |
| type A botulinum toxin | 2 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Lacerations trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Meningitis | 5 | 1 |
| Infection | 4 | 1 |
| Seizure | 4 | 1 |
| Anastomotic leak | 3 | 1 |
| Cerebrospinal fluid leakage | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Lacerations? (236)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Virtual Reality as Active Distraction in Laceration Repair: A Game Changer? | Pediatric emergency care | 2025 | Yes |
| Exploring the influence of perineal biometrics and stiffness measured by elastography during pregnancy on perineal tears : A pilot study. | Journal of gynecology obstetrics and human reproduction | 2025 | Yes |
| Episiotomy to prevent obstetric anal sphincter injuries during instrumental delivery in nulliparous women: a national prospective comparative cohort study. | American journal of obstetrics and gynecology | 2025 | Yes |
| Anxiolysis for laceration repair in children: study protocol for an open-label multicenter adaptive trial (ALICE). | PloS one | 2025 | Yes |
| Mode of delivery and maternal outcome in subsequent delivery after an obstetric anal sphincter injury: a Finnish retrospective cohort study. | BMC pregnancy and childbirth | 2025 | Yes |
Showing 5 of 236 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.