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Condition (MeSH)

Wounds and Injuries

ClinicalTrials.gov lists 18,416 trials for Wounds and Injuries or a narrower condition beneath it. VA Office of Research and Development has the most among industry and government lead sponsors, with 175.

MeSH D014947 Wounds and Injuries C26
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Phase 1 Phase 1 562 Phase 1/2 Phase 1/2 281 Phase 2 Phase 2 895 Phase 2/3 Phase 2/3 220 Phase 3 Phase 3 690 Phase 4 Phase 4 870 Not applicable Not applicable 9,894 Observational Observational 4,983 Phase 1 Phase 1 562 Phase 1/2 Phase 1/2 281 Phase 2 Phase 2 895 Phase 2/3 Phase 2/3 220 Phase 3 Phase 3 690 Phase 4 Phase 4 870 Not applicable Not applicable 9,894 Observational Observational 4,983

Trials per phase (log scale)

2 more sections with rows

2,200 of the 18,416 trials are tagged with Wounds and Injuries itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Wounds and Injuries trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 66 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 1,367

1990: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 1991: 8 trials (Observational 4, Not applicable 2, Phase 3 2) 1992: 9 trials (Observational 6, Not applicable 1, Phase 4 1, Phase 2/3 1) 1993: 7 trials (Observational 4, Not applicable 1, Phase 3 2) 1994: 4 trials (Observational 2, Not applicable 1, Phase 3 1) 1995: 7 trials (Observational 2, Not applicable 2, Phase 2/3 1, Phase 2 2) 1996: 15 trials (Observational 3, Not applicable 4, Phase 4 3, Phase 3 3, Phase 2 1, Phase 1/2 1) 1997: 20 trials (Observational 7, Not applicable 4, Phase 3 2, Phase 2 3, Phase 1/2 1, Phase 1 3) 1998: 28 trials (Observational 10, Not applicable 5, Phase 3 4, Phase 2 9) 1999: 27 trials (Observational 6, Not applicable 9, Phase 4 1, Phase 3 4, Phase 2/3 1, Phase 2 4, Phase 1 2) 2000: 42 trials (Observational 13, Not applicable 13, Phase 4 4, Phase 3 5, Phase 2/3 2, Phase 2 5) 2001: 44 trials (Observational 10, Not applicable 13, Phase 4 4, Phase 3 9, Phase 2 3, Phase 1/2 3, Phase 1 2) 2002: 91 trials (Observational 16, Not applicable 19, Phase 4 16, Phase 3 17, Phase 2/3 2, Phase 2 9, Phase 1/2 4, Phase 1 8) 2003: 139 trials (Observational 25, Not applicable 42, Phase 4 17, Phase 3 18, Phase 2/3 8, Phase 2 21, Phase 1/2 3, Phase 1 5) 2004: 132 trials (Observational 30, Not applicable 46, Phase 4 11, Phase 3 18, Phase 2/3 5, Phase 2 12, Phase 1/2 4, Phase 1 6) 2005: 191 trials (Observational 48, Not applicable 65, Phase 4 18, Phase 3 17, Phase 2/3 6, Phase 2 20, Phase 1/2 8, Phase 1 9) 2006: 214 trials (Observational 53, Not applicable 69, Phase 4 10, Phase 3 30, Phase 2/3 8, Phase 2 24, Phase 1/2 6, Phase 1 14) 2007: 329 trials (Observational 90, Not applicable 109, Phase 4 26, Phase 3 31, Phase 2/3 9, Phase 2 34, Phase 1/2 7, Phase 1 23) 2008: 400 trials (Other 1, Observational 113, Not applicable 147, Phase 4 29, Phase 3 32, Phase 2/3 14, Phase 2 33, Phase 1/2 17, Phase 1 14) 2009: 402 trials (Observational 97, Not applicable 164, Phase 4 36, Phase 3 33, Phase 2/3 9, Phase 2 34, Phase 1/2 14, Phase 1 15) 2010: 454 trials (Observational 125, Not applicable 189, Phase 4 32, Phase 3 35, Phase 2/3 5, Phase 2 44, Phase 1/2 8, Phase 1 16) 2011: 495 trials (Observational 152, Not applicable 195, Phase 4 30, Phase 3 35, Phase 2/3 7, Phase 2 35, Phase 1/2 15, Phase 1 26) 2012: 547 trials (Observational 151, Not applicable 239, Phase 4 41, Phase 3 38, Phase 2/3 5, Phase 2 34, Phase 1/2 13, Phase 1 26) 2013: 601 trials (Observational 136, Not applicable 314, Phase 4 47, Phase 3 18, Phase 2/3 8, Phase 2 46, Phase 1/2 10, Phase 1 22) 2014: 675 trials (Other 1, Observational 169, Not applicable 358, Phase 4 28, Phase 3 26, Phase 2/3 6, Phase 2 45, Phase 1/2 18, Phase 1 24) 2015: 738 trials (Other 1, Observational 182, Not applicable 407, Phase 4 44, Phase 3 22, Phase 2/3 15, Phase 2 35, Phase 1/2 14, Phase 1 18) 2016: 850 trials (Other 2, Observational 245, Not applicable 445, Phase 4 51, Phase 3 22, Phase 2/3 7, Phase 2 48, Phase 1/2 14, Phase 1 16) 2017: 919 trials (Observational 247, Not applicable 525, Phase 4 43, Phase 3 21, Phase 2/3 6, Phase 2 43, Phase 1/2 11, Phase 1 23) 2018: 1,022 trials (Observational 297, Not applicable 585, Phase 4 37, Phase 3 27, Phase 2/3 10, Phase 2 34, Phase 1/2 10, Phase 1 22) 2019: 1,079 trials (Observational 298, Not applicable 608, Phase 4 42, Phase 3 32, Phase 2/3 12, Phase 2 50, Phase 1/2 10, Phase 1 27) 2020: 1,063 trials (Other 1, Observational 327, Not applicable 581, Phase 4 40, Phase 3 22, Phase 2/3 8, Phase 2 40, Phase 1/2 10, Phase 1 34) 2021: 1,349 trials (Observational 387, Not applicable 789, Phase 4 52, Phase 3 26, Phase 2/3 14, Phase 2 26, Phase 1/2 17, Phase 1 38) 2022: 1,294 trials (Observational 363, Not applicable 783, Phase 4 43, Phase 3 27, Phase 2/3 8, Phase 2 30, Phase 1/2 12, Phase 1 28) 2023: 1,326 trials (Observational 360, Not applicable 798, Phase 4 48, Phase 3 28, Phase 2/3 10, Phase 2 39, Phase 1/2 9, Phase 1 34) 2024: 1,367 trials (Other 1, Observational 370, Not applicable 836, Phase 4 37, Phase 3 24, Phase 2/3 10, Phase 2 41, Phase 1/2 11, Phase 1 37) 2025: 1,262 trials (Observational 322, Not applicable 771, Phase 4 38, Phase 3 34, Phase 2/3 7, Phase 2 47, Phase 1/2 15, Phase 1 28)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1,124
2025 1,262
2024 1,367
2023 1,326
2022 1,294
2021 1,349
2020 1,063
2019 1,079
2018 1,022
2017 919

Forecast of the full-year count, planned starts included, not rows of this table: about 1,400 trials starting in 2026 and about 1,300 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,697 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 10,644 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Wounds and Injuries trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 562
Phase 1/2 281
Phase 2 895
Phase 2/3 220
Phase 3 690
Phase 4 870
Not applicable 9,894
Observational 4,983
Expanded access 16
Unknown 5

How many Wounds and Injuries trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1,028
Recruiting 2,212
Enrolling by invitation 228
Active, not recruiting 611
Available 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Wounds and Injuries trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
VA Office of Research and Development 175

Which drugs are being tested for Wounds and Injuries? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
+/- Bupivacaine HCl 87
DEXMEDETOMIDINE 54
PMI-150 (intranasal ketamine) 39

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
[PRP] platelet rich plasma 83
Control (placebo) group 80
acid tranexamic 70
Exercise 69
Ropivacaine 2 % 66

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Wounds and Injuries trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
hospitalization 3,744 3
Study Fracture Related Complication 1,462 2
Other 1,351 9
Pneumonia 1,346 101
Anaemia 448 29

Which publications cover Wounds and Injuries? (2,326)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (51)

MeSH descendants one level down with at least one trial, most trials first.

+41 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages