Condition (MeSH)
Wounds and Injuries
ClinicalTrials.gov lists 18,416 trials for Wounds and Injuries or a narrower condition beneath it. VA Office of Research and Development has the most among industry and government lead sponsors, with 175.
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Trials per phase (log scale)
2 more sections with rows
2,200 of the 18,416 trials are tagged with Wounds and Injuries itself; the rest are tagged with a narrower condition beneath it.
When did Wounds and Injuries trials start? (37)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 66 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
- Other (Expanded access, Unknown)
Top of scale: 1,367
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1,124 |
| 2025 | 1,262 |
| 2024 | 1,367 |
| 2023 | 1,326 |
| 2022 | 1,294 |
| 2021 | 1,349 |
| 2020 | 1,063 |
| 2019 | 1,079 |
| 2018 | 1,022 |
| 2017 | 919 |
Showing 10 of 37 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 1,400 trials starting in 2026 and about 1,300 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 1,697 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 10,644 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Wounds and Injuries trials in? (10)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 562 |
| Phase 1/2 | 281 |
| Phase 2 | 895 |
| Phase 2/3 | 220 |
| Phase 3 | 690 |
| Phase 4 | 870 |
| Not applicable | 9,894 |
| Observational | 4,983 |
| Expanded access | 16 |
| Unknown | 5 |
How many Wounds and Injuries trials are recruiting? (13)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1,028 |
| Recruiting | 2,212 |
| Enrolling by invitation | 228 |
| Active, not recruiting | 611 |
| Available | 4 |
Showing 5 of 13 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Wounds and Injuries trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| VA Office of Research and Development | 175 |
Which drugs are being tested for Wounds and Injuries? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| +/- Bupivacaine HCl | 87 |
| DEXMEDETOMIDINE | 54 |
| PMI-150 (intranasal ketamine) | 39 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| [PRP] platelet rich plasma | 83 |
| Control (placebo) group | 80 |
| acid tranexamic | 70 |
| Exercise | 69 |
| Ropivacaine 2 % | 66 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Wounds and Injuries trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| hospitalization | 3,744 | 3 |
| Study Fracture Related Complication | 1,462 | 2 |
| Other | 1,351 | 9 |
| Pneumonia | 1,346 | 101 |
| Anaemia | 448 | 29 |
Showing 5 of 10 adverse events.
Which publications cover Wounds and Injuries? (2,326)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Cost-effectiveness of specialized trauma care: A systematic review. | Journal of health services research & policy | 2026 | Yes |
| Effectiveness of Exercise in Older Adults Discharged From the ER After Minor Injuries: The CEDeComS Stepped-Wedge Trial. | Journal of the American Geriatrics Society | 2026 | Yes |
| Can screening and referral for posttraumatic stress improve mental health and substance abuse service delivery at trauma centers? Results from a randomized trial. | Injury | 2026 | Yes |
| Characteristics of and Risk Factors for Medical Device-Related Pressure Injuries in Trauma Patients in Intensive Care Units: A Retrospective Case-Control Study. | Western journal of nursing research | 2026 | Yes |
| Acute traumatic pain treatment with ketamine decreased PTSD and anxiety symptoms 6 months post hospital discharge. | The journal of trauma and acute care surgery | 2026 | Yes |
Showing 5 of 2,326 publications.
Sub-conditions in MeSH (51)
MeSH descendants one level down with at least one trial, most trials first.
+41 more sub-conditions
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.