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Condition (MeSH)

Shoulder Injuries

ClinicalTrials.gov lists 1,127 trials for Shoulder Injuries or a narrower condition beneath it. Zimmer Biomet has the most among industry and government lead sponsors, with 21.

MeSH D000070599 Wounds and Injuries C26
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Phase 1 Phase 1 19 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 23 Phase 2/3 Phase 2/3 11 Phase 3 Phase 3 17 Phase 4 Phase 4 56 Not applicable Not applicable 714 Observational Observational 279 Phase 1 Phase 1 19 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 23 Phase 2/3 Phase 2/3 11 Phase 3 Phase 3 17 Phase 4 Phase 4 56 Not applicable Not applicable 714 Observational Observational 279

Trials per phase (log scale)

1 more section with rows

115 of the 1,127 trials are tagged with Shoulder Injuries itself; the rest are tagged with a narrower condition beneath it.

Get the Shoulder Injuries report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Shoulder Injuries trials start? (31)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 5 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 99

1992: 1 trials (Observational 1) 1993: 1 trials (Observational 1) 1998: 1 trials (Observational 1) 1999: 2 trials (Not applicable 2) 2000: 1 trials (Not applicable 1) 2001: 3 trials (Not applicable 2, Phase 1 1) 2002: 2 trials (Phase 4 1, Phase 3 1) 2003: 7 trials (Not applicable 3, Phase 4 2, Phase 3 1, Phase 2 1) 2004: 5 trials (Observational 2, Not applicable 3) 2005: 6 trials (Observational 3, Not applicable 2, Phase 2/3 1) 2006: 5 trials (Observational 3, Not applicable 1, Phase 3 1) 2007: 10 trials (Observational 4, Not applicable 5, Phase 2/3 1) 2008: 19 trials (Observational 4, Not applicable 12, Phase 3 1, Phase 2 2) 2009: 14 trials (Observational 3, Not applicable 7, Phase 3 2, Phase 2 1, Phase 1 1) 2010: 20 trials (Observational 4, Not applicable 11, Phase 4 1, Phase 3 1, Phase 2 1, Phase 1 2) 2011: 24 trials (Observational 5, Not applicable 12, Phase 4 3, Phase 3 1, Phase 2 1, Phase 1 2) 2012: 32 trials (Observational 7, Not applicable 16, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 3) 2013: 35 trials (Observational 4, Not applicable 28, Phase 4 2, Phase 2 1) 2014: 29 trials (Observational 5, Not applicable 20, Phase 4 1, Phase 2 1, Phase 1 2) 2015: 40 trials (Observational 8, Not applicable 27, Phase 4 5) 2016: 46 trials (Observational 11, Not applicable 31, Phase 4 2, Phase 2/3 1, Phase 2 1) 2017: 63 trials (Observational 19, Not applicable 38, Phase 4 4, Phase 2 1, Phase 1 1) 2018: 77 trials (Observational 28, Not applicable 41, Phase 4 4, Phase 3 2, Phase 2/3 1, Phase 2 1) 2019: 78 trials (Observational 19, Not applicable 43, Phase 4 5, Phase 3 3, Phase 2/3 3, Phase 2 4, Phase 1 1) 2020: 88 trials (Observational 20, Not applicable 58, Phase 4 6, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2021: 87 trials (Observational 23, Not applicable 56, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1 1) 2022: 90 trials (Observational 24, Not applicable 59, Phase 4 3, Phase 2 1, Phase 1/2 2, Phase 1 1) 2023: 99 trials (Observational 22, Not applicable 70, Phase 4 4, Phase 2/3 1, Phase 2 1, Phase 1 1) 2024: 86 trials (Observational 17, Not applicable 60, Phase 4 5, Phase 2/3 1, Phase 1/2 2, Phase 1 1) 2025: 78 trials (Observational 17, Not applicable 59, Phase 3 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 70
2025 78
2024 86
2023 99
2022 90
2021 87
2020 88
2019 78
2018 77
2017 63

Showing 10 of 31 earlier years.

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Forecast of the full-year count, planned starts included, not rows of this table: about 87 trials starting in 2026 and about 80 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 91 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 666 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Shoulder Injuries trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 19
Phase 1/2 7
Phase 2 23
Phase 2/3 11
Phase 3 17
Phase 4 56
Not applicable 714
Observational 279
Expanded access 1

How many Shoulder Injuries trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 71
Recruiting 114
Enrolling by invitation 16
Active, not recruiting 45
Completed 584

Showing 5 of 10 statuses.

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Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Shoulder Injuries trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Zimmer Biomet 21
Smith & Nephew, Inc. 9

Which drugs are being tested for Shoulder Injuries? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
+/- Bupivacaine HCl 16
Corticosteroid 7

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
[PRP] platelet rich plasma 22
Exercise 11
Physiotherapy 10
Control (placebo) group 10
Dexamethasone/Dexamethasone acetate 10

Showing 5 of 13 interventions.

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These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Shoulder Injuries trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
General SAE 38 1
Cancer 6 2
Revision 6 1
Shoulder surgery 6 1
Biceps tear/tendon rupture 5 1

Showing 5 of 10 adverse events.

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Which publications cover Shoulder Injuries? (305)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Neck range of motion prognostic factors in association with shoulder and elbow injuries in professional baseball pitchers. Journal of shoulder and elbow surgery 2025 Yes
Physical examination tests in the acute phase of shoulder injuries with negative radiographs: a diagnostic accuracy study. BMC musculoskeletal disorders 2025 Yes
Injury patterns in Swedish elite female and male ice hockey - A cross-sectional comparison of past-season's injuries. Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine 2024 Yes
Knee, Low Back, and Shoulder Problems Among University and Professional Volleyball Players: Playing With Pain. Journal of athletic training 2024 Yes
Developing the Singapore youth shoulder overuse injury prevention program. Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine 2024 Yes

Showing 5 of 305 publications.

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Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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