Gene
DIDO1
DIDO1 is a gene biomarker in the evidence tier "FDA companion diagnostic". This page lists evidence by type: FDA companion diagnostic assertions (1), Assay-provider ledger (5), Target-disease associations (213), and 3 more evidence types, each linked to its source.
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Rows recorded per section (log scale)
6 sections measured, none recorded
FDA companion diagnostic
Evidence over time
Share of that year: what fraction of the papers our biomarker dictionary matched in a year mention DIDO1. The denominator is documents that mention any gene, not every registered document, so improving the matcher moves both halves and never rewrites history. Actionable-biomarker and target-disease-association evidence carries no date in our sources, so it is not on this chart. Publication mentions cover only papers cited by a registered clinical trial, not all of PubMed.
Publication mentions: plotted from 1990 to 2023, the years our matched corpus covers.
DIDO1 has 3 publication mentions across 3 years. That is too few to read as a trend, so the years are listed instead.
The yearly numbers
| Year | Publication mentions | Share of that year |
|---|---|---|
| 2023 | 0 of 11,460 | 0.00% |
| 2022 | 0 of 13,598 | 0.00% |
| 2021 | 1 of 15,045 | 0.01% |
| 2020 | 0 of 14,459 | 0.00% |
| 2019 | 0 of 12,159 | 0.00% |
| 2018 | 0 of 11,854 | 0.00% |
| 2017 | 0 of 11,595 | 0.00% |
| 2016 | 0 of 10,983 | 0.00% |
| 2015 | 0 of 11,395 | 0.00% |
| 2014 | 0 of 10,367 | 0.00% |
Showing 10 of 34 years.
FDA companion diagnostic assertions (1)
Shown in this order: most recent decision first.
| Diagnostic | Source biomarker wording | Manufacturer | Indication | Decision date |
|---|---|---|---|---|
| Idylla CDx MSI Test | DIDO1 | Biocartis US, Inc. | Colorectal Cancer (CRC) | 2025-08-15 |
Assay-provider ledger (5)
Shown in this order: most recent publication first.
| Company | Provider class | Validation | Papers | Most recent publication |
|---|---|---|---|---|
| Biocartis | Diagnostic provider | Clinical validation | 3 | September 01, 2025 |
| Agilent Technologies | Reagent supplier | Clinical validation | 1 | July 24, 2021 |
| DAKO (Carpinteria, CA, USA) - IHC antibodies and Autostainer Link 48 platform | Context dependent | Clinical validation | 1 | July 24, 2021 |
| Diatech Pharmacogenetics | Diagnostic provider | Clinical validation | 1 | July 24, 2021 |
| Qiagen (Hilden, Germany) - Mini Amp DNA extraction kit | Reagent supplier | Clinical validation | 1 | July 24, 2021 |
Target-disease associations (213)
Shown in this order: fixed catalogue order, not ranked.
| Disease | Therapeutic area | Source |
|---|---|---|
| Abnormality of the skeletal system | phenotype | GWAS credible sets |
| Adult-onset autosomal recessive sideroblastic anemia | genetic, familial or congenital disease | Mouse knockout (IMPC) |
| Alpha-thalassemia | genetic, familial or congenital disease | Mouse knockout (IMPC) |
| Alpha-thalassemia - myelodysplastic syndrome | genetic, familial or congenital disease | Mouse knockout (IMPC) |
| Ataxia - pancytopenia | genetic, familial or congenital disease | Mouse knockout (IMPC) |
Showing 5 of 213 associations.
Vendor sourcing (4)
Shown in this order: alphabetical by organization.
| Organization | Role | Tier | Evidence | Citation |
|---|---|---|---|---|
| Ambry Genetics (United States) | Testing lab / CRO (runs the assay) | Clinical-testing interpretation submitted (ClinVar)ClinVar clinical-testing submission | The c.2337G>A (p.M779I) alteration is located in exon 10 (coding exon 8) of the DIDO1 gene. This alteration results from a G to A substitution at nucleotide ... | View ClinVar record SCV003538570.2 |
| Greenwood Genetic Center | Testing lab / CRO (runs the assay) | Clinical-testing interpretation submitted (ClinVar)ClinVar clinical-testing submission | Gene of Uncertain Significance | View ClinVar record SCV007126110.1 |
| Labcorp Holdings Inc. | Testing lab / CRO (runs the assay) | Clinical-testing interpretation submitted (ClinVar)ClinVar clinical-testing submission | No supporting text recorded; see the citation. | View ClinVar record SCV001024872.1 |
| Not resolved to an organization | Diagnostics manufacturer | FDA-authorized companion diagnosticFDA companion diagnostic authorization | Microsatellite instability-High (MSI-H) | View FDA device record |
Trial-cited literature (3)
Shown in this order: newest first, then most cited.
| Publication | Journal | Year | Citations |
|---|---|---|---|
| Genetic insights into biological mechanisms governing human ovarian ageing. | Nature | 2021 | 326 |
| Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | Molecular medicine (Cambridge, Mass.) | 2010 | 108 |
| A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. | Cell | 2009 | 845 |
Organizations publishing (54)
Shown in this order: most papers first.
| Organization | Type | Papers | Years |
|---|---|---|---|
| Duke University | Academic | 1 | 2010 |
| Harvard Medical School | Academic | 1 | 2009 |
| Mass General Brigham | Hospital | 1 | 2009 |
| Broad Institute | Nonprofit | 0 | Not dated |
| Brown University | Academic | 0 | Not dated |
Showing 5 of 54 organizations.
Where DIDO1 appears
- biological_process
- cancer or benign tumor
- cardiovascular disease
- disorder of visual system
- endocrine system disease
- gastrointestinal disease
- genetic, familial or congenital disease
- hematologic disease
- immune system disease
- measurement
- nutritional or metabolic disease
- phenotype
- respiratory or thoracic disease
- urinary system disease
208 diseases touched.
Not on this page
Checked, with nothing recorded for this biomarker: fda biomarker qualification projects, actionable biomarkers, trial mentions, protein variant mentions, human sample screening reference, and literature-extracted relations.