Condition (MeSH)
Abortion, Spontaneous
ClinicalTrials.gov lists 381 trials for Abortion, Spontaneous or a narrower condition beneath it.
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Trials per phase (log scale)
210 of the 381 trials are tagged with Abortion, Spontaneous itself; the rest are tagged with a narrower condition beneath it.
When did Abortion, Spontaneous trials start? (29)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 34
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 18 |
| 2025 | 20 |
| 2024 | 18 |
| 2023 | 17 |
| 2022 | 24 |
| 2021 | 32 |
| 2020 | 34 |
| 2019 | 25 |
| 2018 | 14 |
| 2017 | 18 |
Showing 10 of 29 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 22 trials starting in 2026 and about 20 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 26 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 216 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Abortion, Spontaneous trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 9 |
| Phase 1/2 | 2 |
| Phase 2 | 21 |
| Phase 2/3 | 10 |
| Phase 3 | 26 |
| Phase 4 | 43 |
| Not applicable | 126 |
| Observational | 144 |
How many Abortion, Spontaneous trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 15 |
| Recruiting | 42 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 8 |
| Completed | 184 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Abortion, Spontaneous trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Environmental Health Sciences (NIEHS) | 4 |
| Reprogenetics | 4 |
Which drugs are being tested for Abortion, Spontaneous? (7)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| MisoprostoL | 35 |
| Mifepristone | 8 |
| LOVENOX | 5 |
| Folic (or folinic) acid | 5 |
| INTRALIPID | 3 |
Showing 5 of 7 drugs.
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Letrozol (Femara, Novartis) | 9 |
| Progesterone 8% | 8 |
| EC Aspirin | 5 |
| Vaginal Misoprostol | 4 |
| 1% Metformin | 4 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Abortion, Spontaneous trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| First trimester | 81 | 1 |
| Preeclampsia | 30 | 1 |
| Gestational diabetes mellitus | 20 | 1 |
| neonatal hypoglycemia | 18 | 1 |
| Minor Birth Defects | 8 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Abortion, Spontaneous? (651)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Cabergoline for Lactation Inhibition After Early Second-Trimester Abortion or Pregnancy Loss: A Randomized Controlled Trial. | Obstetrics and gynecology | 2026 | Yes |
| Preconception sleep, pregnancy loss, and adverse pregnancy outcomes among women with a history of pregnancy loss. | Human reproduction (Oxford, England) | 2025 | Yes |
| Vitamin B12 supplementation during pregnancy for maternal and child health outcomes. | The Cochrane database of systematic reviews | 2024 | Yes |
| The experience of breast symptoms after second-trimester abortion or pregnancy loss. | American journal of obstetrics and gynecology | 2024 | Yes |
| A prospective study to evaluate whether serum kisspeptin is a marker predictive of the first-trimester miscarriage of women who conceive in IVF. | Journal of assisted reproduction and genetics | 2024 | Yes |
Showing 5 of 651 publications.
Sub-conditions in MeSH (5)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.