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Condition (MeSH)

Autism Spectrum Disorder

ClinicalTrials.gov lists 2,232 trials for Autism Spectrum Disorder or a narrower condition beneath it.

MeSH D000067877 Mental Disorders F03
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Phase 1 Phase 1 93 Phase 1/2 Phase 1/2 35 Phase 2 Phase 2 208 Phase 2/3 Phase 2/3 25 Phase 3 Phase 3 67 Phase 4 Phase 4 37 Not applicable Not applicable 1,336 Observational Observational 429 Phase 1 Phase 1 93 Phase 1/2 Phase 1/2 35 Phase 2 Phase 2 208 Phase 2/3 Phase 2/3 25 Phase 3 Phase 3 67 Phase 4 Phase 4 37 Not applicable Not applicable 1,336 Observational Observational 429

Trials per phase (log scale)

2 more sections with rows

1,698 of the 2,232 trials are tagged with Autism Spectrum Disorder itself; the rest are tagged with a narrower condition beneath it.

Get the Autism Spectrum Disorder report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Autism Spectrum Disorder trials start? (30)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 12 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 211

1997: 2 trials (Observational 1, Phase 3 1) 1998: 2 trials (Not applicable 2) 1999: 4 trials (Observational 1, Phase 3 3) 2000: 3 trials (Observational 2, Not applicable 1) 2001: 6 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 1/2 1, Phase 1 1) 2002: 7 trials (Observational 1, Phase 3 2, Phase 2 4) 2003: 7 trials (Observational 1, Not applicable 3, Phase 2 1, Phase 1/2 1, Phase 1 1) 2004: 12 trials (Observational 2, Not applicable 2, Phase 3 2, Phase 2/3 1, Phase 2 2, Phase 1/2 2, Phase 1 1) 2005: 19 trials (Observational 2, Not applicable 5, Phase 4 1, Phase 3 2, Phase 2/3 2, Phase 2 5, Phase 1/2 1, Phase 1 1) 2006: 31 trials (Observational 6, Not applicable 9, Phase 4 3, Phase 3 3, Phase 2 5, Phase 1/2 2, Phase 1 3) 2007: 31 trials (Observational 8, Not applicable 10, Phase 4 1, Phase 3 5, Phase 2 2, Phase 1 5) 2008: 35 trials (Observational 7, Not applicable 13, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 8, Phase 1/2 2, Phase 1 2) 2009: 52 trials (Observational 13, Not applicable 20, Phase 4 2, Phase 3 1, Phase 2/3 2, Phase 2 7, Phase 1/2 4, Phase 1 3) 2010: 52 trials (Observational 15, Not applicable 19, Phase 4 3, Phase 3 4, Phase 2/3 2, Phase 2 7, Phase 1 2) 2011: 45 trials (Observational 11, Not applicable 14, Phase 4 4, Phase 3 2, Phase 2 11, Phase 1 3) 2012: 56 trials (Observational 10, Not applicable 21, Phase 3 4, Phase 2/3 3, Phase 2 14, Phase 1/2 1, Phase 1 3) 2013: 74 trials (Observational 20, Not applicable 31, Phase 4 1, Phase 3 4, Phase 2 12, Phase 1 6) 2014: 77 trials (Observational 18, Not applicable 36, Phase 4 4, Phase 2/3 1, Phase 2 13, Phase 1/2 3, Phase 1 2) 2015: 101 trials (Observational 22, Not applicable 60, Phase 4 1, Phase 3 3, Phase 2/3 2, Phase 2 6, Phase 1/2 3, Phase 1 4) 2016: 97 trials (Observational 14, Not applicable 54, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 13, Phase 1/2 2, Phase 1 11) 2017: 74 trials (Observational 15, Not applicable 43, Phase 4 2, Phase 3 2, Phase 2 6, Phase 1/2 1, Phase 1 5) 2018: 115 trials (Observational 25, Not applicable 64, Phase 4 2, Phase 3 6, Phase 2/3 2, Phase 2 12, Phase 1/2 1, Phase 1 3) 2019: 123 trials (Observational 21, Not applicable 78, Phase 4 2, Phase 3 2, Phase 2 10, Phase 1/2 2, Phase 1 8) 2020: 108 trials (Other 1, Observational 22, Not applicable 65, Phase 4 1, Phase 3 2, Phase 2 12, Phase 1/2 1, Phase 1 4) 2021: 149 trials (Observational 32, Not applicable 99, Phase 4 1, Phase 3 3, Phase 2 9, Phase 1/2 1, Phase 1 4) 2022: 159 trials (Observational 26, Not applicable 114, Phase 4 2, Phase 3 2, Phase 2/3 1, Phase 2 8, Phase 1 6) 2023: 204 trials (Observational 34, Not applicable 148, Phase 4 1, Phase 3 2, Phase 2/3 3, Phase 2 13, Phase 1 3) 2024: 211 trials (Observational 37, Not applicable 157, Phase 3 1, Phase 2/3 3, Phase 2 9, Phase 1/2 1, Phase 1 3) 2025: 176 trials (Observational 37, Not applicable 121, Phase 3 1, Phase 2 13, Phase 1/2 2, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 181
2025 176
2024 211
2023 204
2022 159
2021 149
2020 108
2019 123
2018 115
2017 74

Forecast of the full-year count, planned starts included, not rows of this table: about 210 trials starting in 2026 and about 190 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 253 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 1,313 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Autism Spectrum Disorder trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 93
Phase 1/2 35
Phase 2 208
Phase 2/3 25
Phase 3 67
Phase 4 37
Not applicable 1,336
Observational 429
Expanded access 1
Unknown 1

How many Autism Spectrum Disorder trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 132
Recruiting 350
Enrolling by invitation 40
Active, not recruiting 87
Completed 1,203

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Autism Spectrum Disorder? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Aripiprazole 17
Arbaclofen 10
SFX-01 7
Buspirone 7

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Treatment As Usual 34
IM Oxytocin 18
IR Risperidone 15
8IU intranasal oxytocin 11
Control (placebo) group 11

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Autism Spectrum Disorder trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Suicidal ideation 36 6
Schizophrenia 22 1
Suicide attempt 17 2
Aggression 15 7
Bipolar I disorder 12 1

Which publications cover Autism Spectrum Disorder? (1,066)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.

Browse all condition evidence pages