Condition (MeSH)
Radiation Fibrosis Syndrome
ClinicalTrials.gov lists 19 trials for Radiation Fibrosis Syndrome or a narrower condition beneath it. Radiation Therapy Oncology Group has the most among industry and government lead sponsors, with 2.
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Trials per phase
19 of the 19 trials are tagged with Radiation Fibrosis Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Radiation Fibrosis Syndrome trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 2 |
| 2023 | 4 |
| 2021 | 1 |
| 2020 | 1 |
| 2018 | 3 |
| 2013 | 1 |
| 2010 | 1 |
| 2009 | 1 |
| 2008 | 1 |
| 2004 | 1 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Radiation Fibrosis Syndrome trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 8 |
| Not applicable | 7 |
| Observational | 3 |
How many Radiation Fibrosis Syndrome trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 7 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Radiation Fibrosis Syndrome trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Radiation Therapy Oncology Group | 2 |
| Meshalkin Research Institute of Pathology of Circulation | 1 |
| National Cancer Institute (NCI) | 1 |
Which drugs are being tested for Radiation Fibrosis Syndrome? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| CAPTOPRIL | 1 |
| "Endostar" | 1 |
| [68Ga]CBP8 | 1 |
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Low dose losartan | 2 |
| Radiation Therapy | 2 |
| AG chemotherapy | 1 |
| Inhaled budesonide | 1 |
| Hyperbaric Oxygen | 1 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Radiation Fibrosis Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Lymphopenia | 5 | 2 |
| Dyspnoea | 4 | 1 |
| Cough | 3 | 1 |
| Dysphagia | 3 | 1 |
| Neutrophil count decreased | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Radiation Fibrosis Syndrome? (3)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Exploring the mechanisms behind autologous lipotransfer for radiation-induced fibrosis: A systematic review. | PloS one | 2024 | Yes |
| Investigation of the Antihypertrophic and Antifibrotic Effects of Losartan in a Rat Model of Radiation-Induced Heart Disease. | International journal of molecular sciences | 2021 | Yes |
| Pneumonitis and fibrosis after breast cancer radiotherapy: occurrence and treatment-related predictors. | Acta oncologica (Stockholm, Sweden) | 2021 | No |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.