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Condition (MeSH)

Isolated Systolic Hypertension

ClinicalTrials.gov lists 35 trials for Isolated Systolic Hypertension or a narrower condition beneath it. BackBeat Medical Inc has the most among industry and government lead sponsors, with 3.

MeSH D000092244 Cardiovascular Diseases C14
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Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 5 Phase 3 Phase 3 3 Phase 4 Phase 4 7 Not applicable Not applicable 12 Observational Observational 4 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 5 Phase 3 Phase 3 3 Phase 4 Phase 4 7 Not applicable Not applicable 12 Observational Observational 4

Trials per phase

35 of the 35 trials are tagged with Isolated Systolic Hypertension itself; the rest are tagged with a narrower condition beneath it.

Get the Isolated Systolic Hypertension report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Isolated Systolic Hypertension trials start? (21)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 4

1990: 1 trials (Phase 2 1) 2003: 2 trials (Phase 4 1, Phase 3 1) 2004: 2 trials (Phase 4 1, Phase 2 1) 2005: 1 trials (Not applicable 1) 2006: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2007: 1 trials (Phase 4 1) 2008: 1 trials (Phase 2 1) 2009: 1 trials (Phase 4 1) 2011: 2 trials (Not applicable 1, Phase 2 1) 2012: 2 trials (Phase 1 2) 2013: 4 trials (Observational 1, Phase 4 1, Phase 3 1, Phase 2 1) 2014: 1 trials (Not applicable 1) 2018: 1 trials (Observational 1) 2019: 1 trials (Not applicable 1) 2020: 2 trials (Not applicable 2) 2021: 4 trials (Observational 1, Phase 4 1, Phase 1/2 1, Phase 1 1) 2022: 1 trials (Phase 4 1) 2023: 2 trials (Not applicable 2) 2024: 1 trials (Not applicable 1) 2025: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 1
2024 1
2023 2
2022 1
2021 4
2020 2
2019 1
2018 1
2014 1

No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Isolated Systolic Hypertension trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 1
Phase 2 5
Phase 3 3
Phase 4 7
Not applicable 12
Observational 4

How many Isolated Systolic Hypertension trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 5
Completed 20
Terminated 3
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Isolated Systolic Hypertension trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
BackBeat Medical Inc 3
Merck Sharp & Dohme LLC 2
Novartis Pharmaceuticals 2
Daiichi Sankyo 1
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 1

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
HCTZ-hydrochlorothiazide 3
MK-8150 5.0 mg 1
MK-8150 10 mg 1
MK-8150 120 mg 1
MK-8150 100 mg 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Isolated Systolic Hypertension trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Arrhythmia 7 1
Hip surgery 7 1
Non-cardiac chest pain 7 2
Pneumonia 7 2
Syncope 6 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: publications, prevalence, rare-disease identity, and sub-conditions in mesh.

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