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Condition (MeSH)

Mixed Dementias

ClinicalTrials.gov lists 56 trials for Mixed Dementias or a narrower condition beneath it. Hopeful Aging has the most among industry and government lead sponsors, with 4.

MeSH D000093902 Nervous System Diseases C10 F03
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Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 2 Not applicable Not applicable 32 Observational Observational 15 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 2 Not applicable Not applicable 32 Observational Observational 15

Trials per phase (log scale)

56 of the 56 trials are tagged with Mixed Dementias itself; the rest are tagged with a narrower condition beneath it.

Get the Mixed Dementias report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Mixed Dementias trials start? (18)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 10

1995: 1 trials (Phase 3 1) 1998: 2 trials (Phase 3 2) 2000: 1 trials (Observational 1) 2004: 1 trials (Observational 1) 2005: 1 trials (Phase 3 1) 2007: 1 trials (Not applicable 1) 2008: 2 trials (Not applicable 1, Phase 4 1) 2009: 1 trials (Observational 1) 2011: 1 trials (Observational 1) 2015: 1 trials (Observational 1) 2016: 1 trials (Observational 1) 2018: 3 trials (Observational 1, Not applicable 2) 2019: 4 trials (Not applicable 3, Phase 4 1) 2020: 8 trials (Observational 3, Not applicable 5) 2021: 9 trials (Not applicable 8, Phase 2 1) 2022: 3 trials (Not applicable 3) 2023: 5 trials (Observational 2, Not applicable 3) 2024: 10 trials (Observational 3, Not applicable 6, Phase 2/3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2024 10
2023 5
2022 3
2021 9
2020 8
2019 4
2018 3
2016 1
2015 1
2011 1

No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Mixed Dementias trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 1
Phase 2/3 1
Phase 3 5
Phase 4 2
Not applicable 32
Observational 15

How many Mixed Dementias trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 10
Active, not recruiting 3
Completed 31
Terminated 2
Unknown status 10

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Mixed Dementias trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Hopeful Aging 4
Exonhit 2
Bitbrain 1
Gulhane Training and Research Hospital 1
HealthMode Inc. 1

Which drugs are being tested for Mixed Dementias? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Nimodipine 1
ATORVASTATIN 1
IW-6463 1

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
IR Risperidone 3
Galantamine ER 2
Donepezil HCI (drug) 2
No Interventions 1
Cholinesterase Inhibitors (Rivastigmine, Aricept, Galantamine) 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Mixed Dementias trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Death 6 1
Acute Illness or Injury, Sent to hospital 5 1
Failure to thrive 3 2
Hip fracture 3 1
Cerebrovascular accident 2 1

Which publications cover Mixed Dementias? (1)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Statins and cognitive decline in patients with Alzheimer's and mixed dementia: a longitudinal registry-based cohort study. Alzheimer's research & therapy 2023 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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