Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

Oppositional Defiant Disorder

ClinicalTrials.gov lists 85 trials for Oppositional Defiant Disorder or a narrower condition beneath it. Eli Lilly and Company has the most among industry and government lead sponsors, with 3.

MeSH D000096865 Mental Disorders F03
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 2 Phase 3 Phase 3 9 Phase 4 Phase 4 7 Not applicable Not applicable 53 Observational Observational 10 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 2 Phase 3 Phase 3 9 Phase 4 Phase 4 7 Not applicable Not applicable 53 Observational Observational 10

Trials per phase (log scale)

85 of the 85 trials are tagged with Oppositional Defiant Disorder itself; the rest are tagged with a narrower condition beneath it.

Get the Oppositional Defiant Disorder report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Oppositional Defiant Disorder trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 7

1997: 1 trials (Phase 3 1) 1999: 1 trials (Phase 3 1) 2001: 1 trials (Not applicable 1) 2003: 3 trials (Not applicable 2, Phase 3 1) 2004: 3 trials (Observational 1, Phase 4 1, Phase 3 1) 2005: 1 trials (Not applicable 1) 2006: 7 trials (Not applicable 2, Phase 4 2, Phase 3 1, Phase 2 2) 2007: 1 trials (Not applicable 1) 2008: 1 trials (Phase 4 1) 2009: 1 trials (Not applicable 1) 2010: 2 trials (Phase 3 1, Phase 1 1) 2011: 6 trials (Observational 1, Not applicable 3, Phase 4 1, Phase 3 1) 2012: 2 trials (Not applicable 2) 2014: 5 trials (Observational 1, Not applicable 4) 2015: 4 trials (Not applicable 4) 2016: 4 trials (Observational 1, Not applicable 3) 2017: 7 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 1 1) 2018: 3 trials (Not applicable 3) 2019: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2020: 2 trials (Not applicable 1, Phase 1 1) 2021: 2 trials (Not applicable 2) 2022: 6 trials (Not applicable 6) 2023: 2 trials (Not applicable 2) 2024: 7 trials (Not applicable 7) 2025: 6 trials (Observational 1, Not applicable 3, Phase 4 1, Phase 1/2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 6
2024 7
2023 2
2022 6
2021 2
2020 2
2019 3
2018 3
2017 7

No forecast is made for this condition: it averages 4.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 58 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Oppositional Defiant Disorder trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 1
Phase 2 2
Phase 3 9
Phase 4 7
Not applicable 53
Observational 10

How many Oppositional Defiant Disorder trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 12
Active, not recruiting 2
Completed 59
Terminated 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Oppositional Defiant Disorder trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Eli Lilly and Company 3
Janssen Pharmaceutica N.V., Belgium 2
National Institute of Mental Health (NIMH) 2

Which drugs are being tested for Oppositional Defiant Disorder? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
METHYLPHENIDATE 2

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
IR Risperidone 6
Treatment As Usual 5
fatty acids, omega-3 2
Standard Treatment 2
TAU 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Oppositional Defiant Disorder trials report? (6)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal pain upper 2 1
Chest pain 2 1
Abdominal pain 1 1
Furuncle 1 1
Respiratory tract infection 1 1

Which publications cover Oppositional Defiant Disorder? (1)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
START NOW: a cognitive behavioral skills training for adolescent girls with conduct or oppositional defiant disorder - a randomized clinical trial. Journal of child psychology and psychiatry, and allied disciplines 2024 No

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages