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Condition (MeSH)

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

ClinicalTrials.gov lists 21 trials for Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease or a narrower condition beneath it.

MeSH D000098542 Nervous System Diseases C10
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 4 Not applicable Not applicable 2 Observational Observational 12 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 4 Not applicable Not applicable 2 Observational Observational 12

Trials per phase

21 of the 21 trials are tagged with Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease itself; the rest are tagged with a narrower condition beneath it.

Get the Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease report as a PDF

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When did Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease trials start? (9)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2/3
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 5

2014: 1 trials (Observational 1) 2019: 1 trials (Observational 1) 2020: 4 trials (Observational 3, Phase 1 1) 2021: 1 trials (Observational 1) 2022: 2 trials (Phase 3 2) 2023: 1 trials (Phase 3 1) 2024: 5 trials (Observational 3, Not applicable 1, Phase 2/3 1) 2025: 3 trials (Observational 1, Not applicable 1, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 3
2024 5
2023 1
2022 2
2021 1
2020 4
2019 1
2014 1

No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 1
Phase 2/3 1
Phase 3 4
Not applicable 2
Observational 12

How many Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 12
Enrolling by invitation 1
Active, not recruiting 3
Unknown status 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
CRISPR Therapeutics 1
Hoffmann-La Roche 1
UCB Biopharma SRL 1

Which drugs are being tested for Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Rozanolixizumab 1
Prednisone 1
Satralizumab 1

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Azathioprine Pill 2
Calculus bovis sativus 1
data collection 1
Cyclophosphamide and Fludarabine 1
CT103A cells 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease? (2)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD. Journal of neurology, neurosurgery, and psychiatry 2025 Yes
Pain and Headache in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Current pain and headache reports 2025 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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