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Condition (MeSH)

Acute Disease

ClinicalTrials.gov lists 57 trials for Acute Disease or a narrower condition beneath it.

MeSH D000208 Pathological Conditions, Signs and Symptoms C23
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Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 3 Not applicable Not applicable 22 Observational Observational 22 Unknown Unknown 1 Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 3 Not applicable Not applicable 22 Observational Observational 22 Unknown Unknown 1

Trials per phase (log scale)

57 of the 57 trials are tagged with Acute Disease itself; the rest are tagged with a narrower condition beneath it.

Get the Acute Disease report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Acute Disease trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Unknown

Top of scale: 6

1992: 1 trials (Not applicable 1) 2003: 2 trials (Phase 3 2) 2004: 2 trials (Phase 4 1, Phase 2 1) 2005: 1 trials (Not applicable 1) 2007: 1 trials (Phase 2 1) 2008: 1 trials (Phase 2 1) 2009: 2 trials (Not applicable 1, Phase 3 1) 2010: 4 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 2 1) 2011: 1 trials (Not applicable 1) 2012: 2 trials (Observational 1, Not applicable 1) 2014: 1 trials (Not applicable 1) 2015: 6 trials (Observational 2, Not applicable 4) 2016: 2 trials (Observational 2) 2017: 2 trials (Observational 2) 2018: 4 trials (Observational 3, Not applicable 1) 2019: 2 trials (Observational 1, Not applicable 1) 2020: 5 trials (Observational 2, Not applicable 3) 2021: 1 trials (Not applicable 1) 2022: 4 trials (Unknown 1, Observational 1, Not applicable 2) 2023: 1 trials (Observational 1) 2024: 1 trials (Observational 1) 2025: 5 trials (Observational 1, Not applicable 2, Phase 2/3 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 5
2024 1
2023 1
2022 4
2021 1
2020 5
2019 2
2018 4
2017 2

No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 33 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Acute Disease trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 5
Phase 2/3 1
Phase 3 3
Phase 4 3
Not applicable 22
Observational 22
Unknown 1

How many Acute Disease trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 8
Enrolling by invitation 1
Active, not recruiting 2
Completed 28

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Acute Disease trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Pascoe Pharmazeutische Praeparate GmbH 2
Turku University Hospital 2
Antisoma Research 1
Becton, Dickinson and Company 1
Catalan Institute of Health 1

Which drugs are being tested for Acute Disease? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Vosaroxin 1
Vitamin C 1

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Ertapeneme 1
Benzodiazepine 1
rhDNAse 1
Irrigation 1
AS1411 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Acute Disease trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 27 1
Febrile neutropenia 24 1
Stomatitis 11 1
Bacteraemia 9 1
Readmission 9 1

Which publications cover Acute Disease? (7,299)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages