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Condition (MeSH)

Adnexal Diseases

ClinicalTrials.gov lists 5,067 trials for Adnexal Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 194.

MeSH D000291 Urogenital Diseases C12
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Phase 1 Phase 1 928 Phase 1/2 Phase 1/2 411 Phase 2 Phase 2 1,010 Phase 2/3 Phase 2/3 53 Phase 3 Phase 3 369 Phase 4 Phase 4 198 Not applicable Not applicable 1,061 Observational Observational 1,028 Phase 1 Phase 1 928 Phase 1/2 Phase 1/2 411 Phase 2 Phase 2 1,010 Phase 2/3 Phase 2/3 53 Phase 3 Phase 3 369 Phase 4 Phase 4 198 Not applicable Not applicable 1,061 Observational Observational 1,028

Trials per phase (log scale)

1 more section with rows

14 of the 5,067 trials are tagged with Adnexal Diseases itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Adnexal Diseases trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 7 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 303

1990: 1 trials (Phase 1/2 1) 1991: 7 trials (Observational 1, Phase 3 1, Phase 2 3, Phase 1 2) 1992: 7 trials (Observational 4, Phase 2 1, Phase 1 2) 1993: 5 trials (Not applicable 1, Phase 2 4) 1994: 9 trials (Observational 2, Phase 3 1, Phase 1/2 2, Phase 1 4) 1995: 10 trials (Observational 3, Phase 3 2, Phase 2 5) 1996: 17 trials (Observational 2, Phase 3 6, Phase 2 3, Phase 1/2 1, Phase 1 5) 1997: 26 trials (Not applicable 2, Phase 3 3, Phase 2 10, Phase 1/2 4, Phase 1 7) 1998: 43 trials (Observational 2, Not applicable 2, Phase 3 8, Phase 2 20, Phase 1 11) 1999: 54 trials (Observational 8, Phase 3 11, Phase 2/3 1, Phase 2 22, Phase 1/2 2, Phase 1 10) 2000: 51 trials (Observational 6, Not applicable 7, Phase 3 3, Phase 2/3 1, Phase 2 15, Phase 1/2 4, Phase 1 15) 2001: 62 trials (Observational 6, Not applicable 7, Phase 4 2, Phase 3 6, Phase 2/3 1, Phase 2 23, Phase 1/2 3, Phase 1 14) 2002: 67 trials (Observational 10, Not applicable 8, Phase 4 3, Phase 3 11, Phase 2 23, Phase 1/2 3, Phase 1 9) 2003: 90 trials (Observational 15, Not applicable 6, Phase 4 9, Phase 3 6, Phase 2/3 1, Phase 2 34, Phase 1/2 7, Phase 1 12) 2004: 96 trials (Observational 14, Not applicable 13, Phase 4 6, Phase 3 7, Phase 2 33, Phase 1/2 5, Phase 1 18) 2005: 103 trials (Observational 18, Not applicable 14, Phase 4 3, Phase 3 8, Phase 2 36, Phase 1/2 7, Phase 1 17) 2006: 138 trials (Observational 25, Not applicable 24, Phase 4 3, Phase 3 8, Phase 2/3 4, Phase 2 50, Phase 1/2 6, Phase 1 18) 2007: 152 trials (Observational 28, Not applicable 16, Phase 4 7, Phase 3 14, Phase 2/3 1, Phase 2 48, Phase 1/2 8, Phase 1 30) 2008: 139 trials (Observational 19, Not applicable 23, Phase 4 8, Phase 3 14, Phase 2/3 2, Phase 2 40, Phase 1/2 8, Phase 1 25) 2009: 142 trials (Observational 29, Not applicable 21, Phase 4 6, Phase 3 16, Phase 2/3 1, Phase 2 30, Phase 1/2 15, Phase 1 24) 2010: 152 trials (Observational 24, Not applicable 31, Phase 4 7, Phase 3 7, Phase 2/3 2, Phase 2 43, Phase 1/2 10, Phase 1 28) 2011: 150 trials (Observational 31, Not applicable 24, Phase 4 7, Phase 3 13, Phase 2/3 1, Phase 2 27, Phase 1/2 7, Phase 1 40) 2012: 181 trials (Observational 45, Not applicable 34, Phase 4 17, Phase 3 16, Phase 2/3 1, Phase 2 23, Phase 1/2 21, Phase 1 24) 2013: 151 trials (Observational 38, Not applicable 28, Phase 4 12, Phase 3 12, Phase 2 28, Phase 1/2 6, Phase 1 27) 2014: 159 trials (Observational 26, Not applicable 42, Phase 4 12, Phase 3 6, Phase 2/3 2, Phase 2 19, Phase 1/2 16, Phase 1 36) 2015: 189 trials (Observational 33, Not applicable 55, Phase 4 4, Phase 3 11, Phase 2 35, Phase 1/2 13, Phase 1 38) 2016: 230 trials (Observational 55, Not applicable 50, Phase 4 12, Phase 3 11, Phase 2/3 5, Phase 2 39, Phase 1/2 21, Phase 1 37) 2017: 226 trials (Observational 48, Not applicable 46, Phase 4 10, Phase 3 11, Phase 2/3 3, Phase 2 33, Phase 1/2 22, Phase 1 53) 2018: 218 trials (Observational 36, Not applicable 49, Phase 4 9, Phase 3 22, Phase 2/3 1, Phase 2 45, Phase 1/2 16, Phase 1 40) 2019: 232 trials (Observational 48, Not applicable 44, Phase 4 13, Phase 3 18, Phase 2/3 4, Phase 2 33, Phase 1/2 21, Phase 1 51) 2020: 228 trials (Observational 53, Not applicable 57, Phase 4 13, Phase 3 17, Phase 2 32, Phase 1/2 20, Phase 1 36) 2021: 303 trials (Observational 72, Not applicable 73, Phase 4 7, Phase 3 18, Phase 2/3 1, Phase 2 41, Phase 1/2 33, Phase 1 58) 2022: 285 trials (Observational 75, Not applicable 75, Phase 4 4, Phase 3 12, Phase 2/3 1, Phase 2 45, Phase 1/2 20, Phase 1 53) 2023: 277 trials (Observational 63, Not applicable 76, Phase 4 8, Phase 3 12, Phase 2/3 6, Phase 2 41, Phase 1/2 29, Phase 1 42) 2024: 281 trials (Observational 76, Not applicable 60, Phase 4 2, Phase 3 11, Phase 2/3 7, Phase 2 46, Phase 1/2 23, Phase 1 56) 2025: 287 trials (Observational 63, Not applicable 83, Phase 4 8, Phase 3 23, Phase 2/3 4, Phase 2 35, Phase 1/2 30, Phase 1 41)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 253
2025 287
2024 281
2023 277
2022 285
2021 303
2020 228
2019 232
2018 218
2017 226

Forecast of the full-year count, planned starts included, not rows of this table: about 310 trials starting in 2026 and about 290 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 582 trials still running at the 2026-10-09 snapshot; registered median of 34 months across 2,892 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Adnexal Diseases trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 928
Phase 1/2 411
Phase 2 1,010
Phase 2/3 53
Phase 3 369
Phase 4 198
Not applicable 1,061
Observational 1,028
Expanded access 9

How many Adnexal Diseases trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 213
Recruiting 701
Enrolling by invitation 14
Active, not recruiting 284
Available 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Adnexal Diseases trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 194
Gynecologic Oncology Group 78
AstraZeneca 66
Eli Lilly and Company 31
Pfizer 29

Which drugs are being tested for Adnexal Diseases? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
(nab)-paclitaxel 341
PEMBROLIZUMAB 104
TOPOTECAN 93
Cytoxan 91

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
or carboplatin 318
Bevacizumab 1 186
1% Metformin 147
Gemcitabine/Gemzar 100
Arm A - Olaparib 89

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Adnexal Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Vomiting 1,208 251
Abdominal pain 961 201
Nausea 902 237
Small intestinal obstruction 896 177
Anaemia 879 139

Which publications cover Adnexal Diseases? (86)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages