Condition (MeSH)
Affective Disorders, Psychotic
ClinicalTrials.gov lists 26 trials for Affective Disorders, Psychotic or a narrower condition beneath it. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. has the most among industry and government lead sponsors, with 5.
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Trials per phase
26 of the 26 trials are tagged with Affective Disorders, Psychotic itself; the rest are tagged with a narrower condition beneath it.
When did Affective Disorders, Psychotic trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2024 | 2 |
| 2022 | 2 |
| 2021 | 1 |
| 2020 | 2 |
| 2016 | 1 |
| 2015 | 2 |
| 2014 | 2 |
| 2012 | 2 |
Showing 10 of 16 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Affective Disorders, Psychotic trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2/3 | 1 |
| Phase 3 | 7 |
| Phase 4 | 1 |
| Not applicable | 13 |
| Observational | 3 |
How many Affective Disorders, Psychotic trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 3 |
| Completed | 21 |
| Terminated | 1 |
| Withdrawn | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Affective Disorders, Psychotic trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 5 |
| VA Office of Research and Development | 3 |
| Otsuka Pharmaceutical Development & Commercialization, Inc. | 1 |
| US Department of Veterans Affairs | 1 |
Which drugs are being tested for Affective Disorders, Psychotic? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Brexpiprazole | 1 |
| Mifepristone | 1 |
Interventions as named in the registry (6)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Topiramate IR | 2 |
| ER Paliperidone | 2 |
| Treatment As Usual | 2 |
| IR (Immediate-Release) quetiapine fumarate (drug) | 1 |
| Paliperidone Extended Release (ER) | 1 |
Showing 5 of 6 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Affective Disorders, Psychotic trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Psychaitric decompensation requiring hospitalization | 1 | 1 |
Which publications cover Affective Disorders, Psychotic? (42)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Specialised early intervention teams (extended time) for recent-onset psychosis. | The Cochrane database of systematic reviews | 2020 | Yes |
| Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene. | Biological psychiatry | 2019 | Yes |
| HPA axis in psychotic major depression and schizophrenia spectrum disorders: Cortisol, clinical symptomatology, and cognition. | Schizophrenia research | 2019 | Yes |
| Social Recovery Therapy in improving activity and social outcomes in early psychosis: Current evidence and longer term outcomes. | Schizophrenia research | 2019 | Yes |
| Auditory steady-state EEG response across the schizo-bipolar spectrum. | Schizophrenia research | 2019 | Yes |
Showing 5 of 42 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.