Condition (MeSH)
Alcoholism
ClinicalTrials.gov lists 1,663 trials for Alcoholism or a narrower condition beneath it. National Institute on Alcohol Abuse and Alcoholism (NIAAA) has the most among industry and government lead sponsors, with 70.
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Trials per phase (log scale)
1,663 of the 1,663 trials are tagged with Alcoholism itself; the rest are tagged with a narrower condition beneath it.
When did Alcoholism trials start? (33)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 15 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 105
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 94 |
| 2025 | 90 |
| 2024 | 105 |
| 2023 | 98 |
| 2022 | 86 |
| 2021 | 90 |
| 2020 | 76 |
| 2019 | 100 |
| 2018 | 71 |
| 2017 | 69 |
Showing 10 of 33 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 110 trials starting in 2026 and about 95 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 196 trials still running at the 2026-10-09 snapshot; registered median of 30 months across 1,080 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Alcoholism trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 123 |
| Phase 1/2 | 42 |
| Phase 2 | 304 |
| Phase 2/3 | 37 |
| Phase 3 | 86 |
| Phase 4 | 125 |
| Not applicable | 757 |
| Observational | 189 |
How many Alcoholism trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 74 |
| Recruiting | 214 |
| Enrolling by invitation | 13 |
| Active, not recruiting | 55 |
| Completed | 1,016 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Alcoholism trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 70 |
| VA Office of Research and Development | 47 |
Which drugs are being tested for Alcoholism? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Cannabidiol | 11 |
| Nalmefene | 11 |
| PMI-150 (intranasal ketamine) | 10 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| IM naltrexone | 85 |
| 98% dehydrated alcohol | 31 |
| Acomprosate | 25 |
| Topiramate IR | 21 |
| Treatment As Usual | 21 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Alcoholism trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hospitalization | 173 | 11 |
| hosapitalizations | 152 | 1 |
| Alcoholism | 84 | 11 |
| Increased drinking from baseline | 65 | 1 |
| Suicidal ideation | 29 | 12 |
Showing 5 of 10 adverse events.
Which publications cover Alcoholism? (2,285)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Efficacy of a personalised alcohol approach bias modification smartphone app in people accessing outpatient alcohol use disorder treatment: A randomised controlled trial. | Addiction (Abingdon, England) | 2026 | Yes |
| Implementing pragmatic case finding to address alcohol use in general practice: a mixed methods feasibility study. | Scandinavian journal of primary health care | 2026 | Yes |
| A Need for Strategies to Reduce Alcohol Use After Metabolic and Bariatric Surgery: Technology-Based Intervention and Study Protocol for a Pilot Randomized Controlled Trial. | JMIR research protocols | 2026 | Yes |
| Effect of high-dose baclofen on post-traumatic stress disorder symptoms five years after hospitalization among critically ill patients with unhealthy alcohol use. | Scientific reports | 2026 | Yes |
| Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. | JAMA psychiatry | 2025 | Yes |
Showing 5 of 2,285 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.