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Condition (MeSH)

Antisocial Personality Disorder

ClinicalTrials.gov lists 67 trials for Antisocial Personality Disorder or a narrower condition beneath it.

MeSH D000987 Mental Disorders F03
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Phase 1 Phase 1 2 Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 5 Phase 4 Phase 4 4 Not applicable Not applicable 31 Observational Observational 22 Phase 1 Phase 1 2 Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 5 Phase 4 Phase 4 4 Not applicable Not applicable 31 Observational Observational 22

Trials per phase

67 of the 67 trials are tagged with Antisocial Personality Disorder itself; the rest are tagged with a narrower condition beneath it.

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When did Antisocial Personality Disorder trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 6

1991: 1 trials (Not applicable 1) 1998: 1 trials (Phase 4 1) 2001: 1 trials (Observational 1) 2003: 1 trials (Phase 2/3 1) 2004: 1 trials (Observational 1) 2005: 2 trials (Observational 2) 2006: 2 trials (Observational 1, Phase 4 1) 2007: 4 trials (Observational 4) 2008: 2 trials (Observational 1, Phase 2 1) 2009: 2 trials (Observational 1, Phase 2 1) 2010: 1 trials (Phase 2/3 1) 2011: 5 trials (Observational 2, Not applicable 1, Phase 2/3 1, Phase 1 1) 2012: 1 trials (Phase 2/3 1) 2013: 1 trials (Observational 1) 2014: 1 trials (Phase 2 1) 2015: 4 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 2/3 1) 2016: 5 trials (Not applicable 3, Phase 4 1, Phase 1 1) 2017: 6 trials (Observational 1, Not applicable 5) 2018: 3 trials (Observational 2, Not applicable 1) 2019: 3 trials (Not applicable 3) 2020: 4 trials (Observational 1, Not applicable 3) 2021: 2 trials (Observational 1, Not applicable 1) 2022: 2 trials (Not applicable 2) 2023: 4 trials (Observational 2, Not applicable 2) 2024: 3 trials (Not applicable 3) 2025: 2 trials (Not applicable 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2025 2
2024 3
2023 4
2022 2
2021 2
2020 4
2019 3
2018 3
2017 6

No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 9 trials still running at the 2026-10-09 snapshot; registered median of 30 months across 39 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Antisocial Personality Disorder trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 2 3
Phase 2/3 5
Phase 4 4
Not applicable 31
Observational 22

How many Antisocial Personality Disorder trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 7
Active, not recruiting 4
Completed 39
Terminated 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Antisocial Personality Disorder trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
GE Healthcare 3
National Institute of Mental Health (NIMH) 3

Which drugs are being tested for Antisocial Personality Disorder? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Naratriptan 1

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Treatment As Usual 6
fatty acids, omega-3 2
Cognitive Remediation 2
IM Oxytocin 1
Standard Care 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Antisocial Personality Disorder trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Premature delivery 24 1
Premature baby 17 1
Drug withdrawal syndrome neonatal 9 1
Death 6 1
Neonatal respiratory distress syndrome 6 1

Which publications cover Antisocial Personality Disorder? (154)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Psychopathy and dangerousness: An umbrella review and meta-analysis. Clinical psychology review 2023 Yes
The efficacy of the PSYCHOPATHY.COMP program in reducing psychopathic traits: A controlled trial with male detained youth. Journal of consulting and clinical psychology 2021 Yes
Psychopathy is associated with an exaggerated attention bottleneck: EEG and behavioral evidence from a dual-task paradigm. Cognitive, affective & behavioral neuroscience 2021 Yes
Psychological interventions for antisocial personality disorder. The Cochrane database of systematic reviews 2020 Yes
Pharmacological interventions for antisocial personality disorder. The Cochrane database of systematic reviews 2020 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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