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Condition (MeSH)

Marijuana Abuse

ClinicalTrials.gov lists 564 trials for Marijuana Abuse or a narrower condition beneath it. National Institute on Drug Abuse (NIDA) has the most among industry and government lead sponsors, with 17.

MeSH D002189 Chemically-Induced Disorders C25 F03
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Phase 1 Phase 1 123 Phase 1/2 Phase 1/2 34 Phase 2 Phase 2 108 Phase 2/3 Phase 2/3 19 Phase 3 Phase 3 28 Phase 4 Phase 4 22 Not applicable Not applicable 148 Observational Observational 82 Phase 1 Phase 1 123 Phase 1/2 Phase 1/2 34 Phase 2 Phase 2 108 Phase 2/3 Phase 2/3 19 Phase 3 Phase 3 28 Phase 4 Phase 4 22 Not applicable Not applicable 148 Observational Observational 82

Trials per phase

558 of the 564 trials are tagged with Marijuana Abuse itself; the rest are tagged with a narrower condition beneath it.

Get the Marijuana Abuse report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Marijuana Abuse trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 4 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 42

1999: 1 trials (Phase 2/3 1) 2000: 4 trials (Not applicable 1, Phase 4 1, Phase 3 1, Phase 2 1) 2001: 4 trials (Phase 4 1, Phase 1/2 3) 2002: 1 trials (Phase 1/2 1) 2003: 2 trials (Phase 1/2 2) 2004: 17 trials (Observational 3, Not applicable 2, Phase 3 1, Phase 2 9, Phase 1/2 1, Phase 1 1) 2005: 12 trials (Observational 2, Not applicable 1, Phase 2 7, Phase 1/2 1, Phase 1 1) 2006: 11 trials (Not applicable 2, Phase 4 1, Phase 2 4, Phase 1 4) 2007: 8 trials (Observational 1, Not applicable 4, Phase 1 3) 2008: 17 trials (Observational 1, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2 3, Phase 1/2 2, Phase 1 6) 2009: 23 trials (Observational 3, Not applicable 5, Phase 4 1, Phase 2/3 1, Phase 2 7, Phase 1/2 3, Phase 1 3) 2010: 13 trials (Observational 3, Not applicable 2, Phase 4 1, Phase 2/3 2, Phase 1/2 4, Phase 1 1) 2011: 11 trials (Observational 1, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2 2, Phase 1/2 1, Phase 1 2) 2012: 16 trials (Observational 2, Not applicable 2, Phase 2/3 4, Phase 2 5, Phase 1 3) 2013: 15 trials (Observational 2, Not applicable 7, Phase 4 1, Phase 2/3 1, Phase 2 3, Phase 1 1) 2014: 17 trials (Observational 2, Not applicable 4, Phase 3 1, Phase 2 2, Phase 1/2 2, Phase 1 6) 2015: 16 trials (Observational 3, Not applicable 5, Phase 4 1, Phase 2 1, Phase 1/2 1, Phase 1 5) 2016: 30 trials (Observational 8, Not applicable 8, Phase 4 1, Phase 2 4, Phase 1 9) 2017: 23 trials (Observational 1, Not applicable 6, Phase 4 1, Phase 2/3 2, Phase 2 4, Phase 1/2 2, Phase 1 7) 2018: 28 trials (Observational 6, Not applicable 6, Phase 4 1, Phase 3 1, Phase 2/3 3, Phase 2 6, Phase 1 5) 2019: 24 trials (Observational 4, Not applicable 7, Phase 3 4, Phase 2 2, Phase 1 7) 2020: 32 trials (Observational 7, Not applicable 7, Phase 4 4, Phase 2/3 1, Phase 2 7, Phase 1 6) 2021: 40 trials (Observational 6, Not applicable 9, Phase 4 3, Phase 3 4, Phase 2/3 1, Phase 2 6, Phase 1 11) 2022: 42 trials (Observational 7, Not applicable 16, Phase 3 2, Phase 2 5, Phase 1/2 3, Phase 1 9) 2023: 41 trials (Observational 5, Not applicable 11, Phase 3 9, Phase 2/3 2, Phase 2 7, Phase 1/2 1, Phase 1 6) 2024: 29 trials (Observational 6, Not applicable 10, Phase 2 6, Phase 1/2 1, Phase 1 6) 2025: 39 trials (Observational 6, Not applicable 13, Phase 4 2, Phase 3 2, Phase 2 4, Phase 1/2 2, Phase 1 10)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 42
2025 39
2024 29
2023 41
2022 42
2021 40
2020 32
2019 24
2018 28
2017 23

Forecast of the full-year count, planned starts included, not rows of this table: about 48 trials starting in 2026 and about 40 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 70 trials still running at the 2026-10-09 snapshot; registered median of 28 months across 341 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Marijuana Abuse trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 123
Phase 1/2 34
Phase 2 108
Phase 2/3 19
Phase 3 28
Phase 4 22
Not applicable 148
Observational 82

How many Marijuana Abuse trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 29
Recruiting 80
Enrolling by invitation 7
Active, not recruiting 18
Completed 313

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Marijuana Abuse trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute on Drug Abuse (NIDA) 17
Apurano Pharmaceuticals GmbH 8

Which drugs are being tested for Marijuana Abuse? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Marijuana 56
Dronabinol 41
Cannabidiol 29
Nicotine Patch 6

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Sativex Low Dose 12
Adezunap 8
Medical Cannabis 6
Treatment As Usual 6
N Acetylcysteine 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Marijuana Abuse trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Boot Camp, Detention, Incarceration 13 1
Hospitalization 9 1
Hospitatlization or Residential Treatment for Mental Health 8 1
Psychosis 8 3
Residential Treatment for Substance Use 7 1

Which publications cover Marijuana Abuse? (281)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors 2025 Yes
Clinician's perceptions and experiences with tobacco treatment in people who use cannabis: a qualitative study. Substance abuse treatment, prevention, and policy 2025 Yes
N-acetylcysteine for youth cannabis use disorder: randomized controlled trial main findings. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Yes
Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Yes
User-centered Design of an Adjunct Smartphone App to Reduce Cannabis Use among Youth Diverted from the Juvenile Legal System. Research on child and adolescent psychopathology 2025 Yes

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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