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Condition (MeSH)

Carbon Monoxide Poisoning

ClinicalTrials.gov lists 43 trials for Carbon Monoxide Poisoning or a narrower condition beneath it. Nonin Medical, Inc has the most among industry and government lead sponsors, with 3.

MeSH D002249 Chemically-Induced Disorders C25
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Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 1 Phase 3 Phase 3 3 Phase 4 Phase 4 2 Not applicable Not applicable 8 Observational Observational 26 Unknown Unknown 1 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 1 Phase 3 Phase 3 3 Phase 4 Phase 4 2 Not applicable Not applicable 8 Observational Observational 26 Unknown Unknown 1

Trials per phase (log scale)

43 of the 43 trials are tagged with Carbon Monoxide Poisoning itself; the rest are tagged with a narrower condition beneath it.

Get the Carbon Monoxide Poisoning report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Carbon Monoxide Poisoning trials start? (17)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Unknown

Top of scale: 4

2005: 1 trials (Observational 1) 2006: 1 trials (Observational 1) 2007: 3 trials (Observational 2, Phase 4 1) 2009: 3 trials (Observational 1, Not applicable 2) 2012: 2 trials (Observational 1, Not applicable 1) 2013: 1 trials (Phase 3 1) 2014: 1 trials (Observational 1) 2016: 4 trials (Unknown 1, Observational 2, Phase 1/2 1) 2017: 3 trials (Observational 2, Not applicable 1) 2018: 1 trials (Observational 1) 2019: 3 trials (Observational 2, Not applicable 1) 2020: 4 trials (Observational 4) 2021: 2 trials (Observational 1, Not applicable 1) 2022: 4 trials (Observational 3, Phase 2 1) 2023: 2 trials (Observational 1, Not applicable 1) 2025: 3 trials (Observational 1, Not applicable 1, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2025 3
2023 2
2022 4
2021 2
2020 4
2019 3
2018 1
2017 3
2016 4

No forecast is made for this condition: it averages 2.2 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Carbon Monoxide Poisoning trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 2
Phase 2 1
Phase 3 3
Phase 4 2
Not applicable 8
Observational 26
Unknown 1

How many Carbon Monoxide Poisoning trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 5
Enrolling by invitation 1
Completed 14
Terminated 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Carbon Monoxide Poisoning trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Nonin Medical, Inc 3

Which drugs are being tested for Carbon Monoxide Poisoning? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
L Carnitine 1

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Hyperbaric Oxygen 7
Dexamethasone and N-acetylcysteine (NAC) 1
Human cord blood mononuclear cell 1
Dexamethasone/Dexamethasone acetate 1
18F-FP-DTBZ (18F-AV-133) 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Carbon Monoxide Poisoning? (38)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Efficacy of different oxygen delivery methods in carbon monoxide poisoning: a prospective observational study. Inhalation toxicology 2025 Yes
Comparing high-flow nasal oxygen therapy and normobaric oxygen therapy on the treatment of carbon monoxide poisoning. Medizinische Klinik, Intensivmedizin und Notfallmedizin 2024 Yes
Mortality Risks and Causes in Previous Carbon Monoxide Poisoning: A Nationwide Population-Based Cohort Study. Critical care medicine 2024 Yes
International Multicenter Registry for Hyperbaric Oxygen Therapy: Results through June 2021. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2022 Yes
CPAP versus HFNC use in carbon monoxide poisoning. The American journal of emergency medicine 2021 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages