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Condition (MeSH)

Cecal Diseases

ClinicalTrials.gov lists 482 trials for Cecal Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 9.

MeSH D002429 Digestive System Diseases C06
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Phase 1 Phase 1 29 Phase 1/2 Phase 1/2 6 Phase 2 Phase 2 30 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 19 Phase 4 Phase 4 33 Not applicable Not applicable 192 Observational Observational 172 Phase 1 Phase 1 29 Phase 1/2 Phase 1/2 6 Phase 2 Phase 2 30 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 19 Phase 4 Phase 4 33 Not applicable Not applicable 192 Observational Observational 172

Trials per phase (log scale)

1 of the 482 trials are tagged with Cecal Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Cecal Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Cecal Diseases trials start? (32)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 34

1994: 1 trials (Phase 3 1) 1996: 1 trials (Phase 2 1) 1997: 1 trials (Phase 1 1) 1998: 1 trials (Phase 1 1) 1999: 3 trials (Phase 1 3) 2000: 5 trials (Observational 2, Phase 1 3) 2001: 6 trials (Observational 3, Phase 3 1, Phase 1 2) 2002: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 2003: 7 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 3 1, Phase 2 1, Phase 1 1) 2004: 7 trials (Not applicable 2, Phase 4 2, Phase 3 2, Phase 2 1) 2005: 7 trials (Observational 4, Phase 4 3) 2006: 7 trials (Observational 2, Not applicable 3, Phase 3 1, Phase 2 1) 2007: 11 trials (Observational 4, Not applicable 4, Phase 3 1, Phase 1 2) 2008: 13 trials (Observational 5, Not applicable 5, Phase 4 1, Phase 3 1, Phase 1 1) 2009: 21 trials (Observational 6, Not applicable 8, Phase 4 1, Phase 3 3, Phase 2 2, Phase 1 1) 2010: 10 trials (Observational 4, Not applicable 4, Phase 4 1, Phase 3 1) 2011: 11 trials (Observational 3, Not applicable 4, Phase 4 2, Phase 2 2) 2012: 15 trials (Observational 7, Not applicable 6, Phase 4 1, Phase 2 1) 2013: 15 trials (Observational 5, Not applicable 7, Phase 3 2, Phase 2 1) 2014: 12 trials (Observational 4, Not applicable 8) 2015: 26 trials (Observational 12, Not applicable 9, Phase 4 2, Phase 3 1, Phase 2 1, Phase 1 1) 2016: 27 trials (Observational 9, Not applicable 11, Phase 4 3, Phase 2 2, Phase 1/2 1, Phase 1 1) 2017: 34 trials (Observational 12, Not applicable 14, Phase 4 2, Phase 2 4, Phase 1/2 2) 2018: 21 trials (Observational 7, Not applicable 9, Phase 4 3, Phase 2/3 1, Phase 2 1) 2019: 24 trials (Observational 8, Not applicable 11, Phase 4 3, Phase 2 2) 2020: 32 trials (Observational 16, Not applicable 13, Phase 4 1, Phase 1 2) 2021: 32 trials (Observational 13, Not applicable 11, Phase 3 1, Phase 2 3, Phase 1/2 1, Phase 1 3) 2022: 22 trials (Observational 11, Not applicable 6, Phase 4 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2023: 34 trials (Observational 10, Not applicable 16, Phase 4 2, Phase 3 1, Phase 2 2, Phase 1/2 1, Phase 1 2) 2024: 21 trials (Observational 9, Not applicable 9, Phase 4 1, Phase 3 1, Phase 2 1) 2025: 24 trials (Observational 8, Not applicable 13, Phase 4 2, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 22
2025 24
2024 21
2023 34
2022 22
2021 32
2020 32
2019 24
2018 21
2017 34

Forecast of the full-year count, planned starts included, not rows of this table: about 27 trials starting in 2026 and about 25 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 34 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 307 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Cecal Diseases trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 29
Phase 1/2 6
Phase 2 30
Phase 2/3 1
Phase 3 19
Phase 4 33
Not applicable 192
Observational 172

How many Cecal Diseases trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 15
Recruiting 49
Enrolling by invitation 1
Active, not recruiting 17
Completed 280

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Cecal Diseases trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 9
Turku University Hospital 7
Zagazig University 4

Which drugs are being tested for Cecal Diseases? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
OXALIPLATIN 10
Irinotecan 5
Calcium Leucovorin 5
"Capecitabine" 4

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Mitomycin C 0.02% 10
Ertapeneme 6
Fluorouracile 6
Ropivacaine 2 % 4
PO Morphine 4

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Cecal Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Appendiceal perforation 130 1
Low Hemoglobin 71 1
Negative appendicitis 47 1
Lymphopenia 45 1
Abdominal pain 40 6

Which publications cover Cecal Diseases? (17)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Histopathological features of incidental appendectomy specimens obtained from living liver donors. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2020 Yes
Laparoscopic Surgery or Conservative Treatment for Appendiceal Abscess in Adults? A Randomized Controlled Trial. Annals of surgery 2015 Yes
Ruptured uterus and bowel injury from manual removal of placenta: a case report. The Nigerian postgraduate medical journal 2012 Yes
Early versus late surgery for ileo-caecal Crohn's disease. Alimentary pharmacology & therapeutics 2007 Yes
Increased risk of ischemic bowel complications during treatment with bevacizumab after pelvic irradiation: report of three cases. International journal of radiation oncology, biology, physics 2006 Yes

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages