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Condition (MeSH)

Cerebrovascular Disorders

ClinicalTrials.gov lists 12,768 trials for Cerebrovascular Disorders or a narrower condition beneath it. VA Office of Research and Development has the most among industry and government lead sponsors, with 95.

MeSH D002561 Nervous System Diseases C10 C14
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Phase 1 Phase 1 415 Phase 1/2 Phase 1/2 215 Phase 2 Phase 2 778 Phase 2/3 Phase 2/3 164 Phase 3 Phase 3 729 Phase 4 Phase 4 538 Not applicable Not applicable 6,099 Observational Observational 3,815 Phase 1 Phase 1 415 Phase 1/2 Phase 1/2 215 Phase 2 Phase 2 778 Phase 2/3 Phase 2/3 164 Phase 3 Phase 3 729 Phase 4 Phase 4 538 Not applicable Not applicable 6,099 Observational Observational 3,815

Trials per phase (log scale)

2 more sections with rows

433 of the 12,768 trials are tagged with Cerebrovascular Disorders itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Cerebrovascular Disorders trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 38 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 1,028

1990: 5 trials (Observational 4, Phase 2 1) 1991: 8 trials (Observational 8) 1992: 7 trials (Observational 4, Not applicable 1, Phase 3 2) 1993: 11 trials (Observational 6, Phase 4 1, Phase 3 3, Phase 1 1) 1994: 9 trials (Observational 6, Phase 4 1, Phase 3 1, Phase 2 1) 1995: 13 trials (Observational 7, Not applicable 1, Phase 3 3, Phase 2/3 1, Phase 2 1) 1996: 11 trials (Observational 7, Phase 4 2, Phase 3 1, Phase 2/3 1) 1997: 11 trials (Observational 6, Not applicable 1, Phase 4 3, Phase 3 1) 1998: 21 trials (Observational 9, Not applicable 2, Phase 4 3, Phase 3 4, Phase 2/3 1, Phase 2 2) 1999: 26 trials (Observational 13, Not applicable 2, Phase 4 2, Phase 3 4, Phase 2 5) 2000: 45 trials (Observational 21, Not applicable 4, Phase 4 1, Phase 3 8, Phase 2/3 1, Phase 2 10) 2001: 53 trials (Observational 22, Not applicable 8, Phase 4 4, Phase 3 7, Phase 2 11, Phase 1/2 1) 2002: 76 trials (Observational 23, Not applicable 19, Phase 4 4, Phase 3 13, Phase 2/3 1, Phase 2 10, Phase 1/2 2, Phase 1 4) 2003: 108 trials (Observational 31, Not applicable 14, Phase 4 11, Phase 3 16, Phase 2/3 3, Phase 2 19, Phase 1/2 7, Phase 1 7) 2004: 92 trials (Observational 25, Not applicable 17, Phase 4 14, Phase 3 17, Phase 2/3 1, Phase 2 15, Phase 1 3) 2005: 148 trials (Observational 36, Not applicable 33, Phase 4 18, Phase 3 23, Phase 2/3 5, Phase 2 18, Phase 1/2 6, Phase 1 9) 2006: 157 trials (Observational 48, Not applicable 38, Phase 4 14, Phase 3 17, Phase 2/3 2, Phase 2 23, Phase 1/2 2, Phase 1 13) 2007: 188 trials (Observational 58, Not applicable 42, Phase 4 20, Phase 3 18, Phase 2/3 5, Phase 2 17, Phase 1/2 12, Phase 1 16) 2008: 225 trials (Observational 56, Not applicable 72, Phase 4 15, Phase 3 19, Phase 2/3 8, Phase 2 28, Phase 1/2 10, Phase 1 17) 2009: 245 trials (Observational 63, Not applicable 73, Phase 4 24, Phase 3 23, Phase 2/3 8, Phase 2 30, Phase 1/2 12, Phase 1 12) 2010: 271 trials (Observational 87, Not applicable 89, Phase 4 18, Phase 3 19, Phase 2/3 6, Phase 2 23, Phase 1/2 6, Phase 1 23) 2011: 302 trials (Observational 100, Not applicable 98, Phase 4 13, Phase 3 13, Phase 2/3 4, Phase 2 39, Phase 1/2 16, Phase 1 19) 2012: 369 trials (Observational 119, Not applicable 125, Phase 4 18, Phase 3 35, Phase 2/3 4, Phase 2 32, Phase 1/2 13, Phase 1 23) 2013: 425 trials (Observational 112, Not applicable 193, Phase 4 21, Phase 3 31, Phase 2/3 5, Phase 2 30, Phase 1/2 14, Phase 1 19) 2014: 506 trials (Observational 156, Not applicable 235, Phase 4 26, Phase 3 22, Phase 2/3 8, Phase 2 30, Phase 1/2 12, Phase 1 17) 2015: 517 trials (Observational 166, Not applicable 249, Phase 4 27, Phase 3 23, Phase 2/3 6, Phase 2 23, Phase 1/2 8, Phase 1 15) 2016: 550 trials (Other 1, Observational 167, Not applicable 267, Phase 4 23, Phase 3 19, Phase 2/3 10, Phase 2 36, Phase 1/2 8, Phase 1 19) 2017: 577 trials (Observational 174, Not applicable 304, Phase 4 20, Phase 3 26, Phase 2/3 7, Phase 2 28, Phase 1/2 2, Phase 1 16) 2018: 668 trials (Observational 209, Not applicable 344, Phase 4 26, Phase 3 35, Phase 2/3 7, Phase 2 25, Phase 1/2 8, Phase 1 14) 2019: 706 trials (Observational 225, Not applicable 369, Phase 4 19, Phase 3 22, Phase 2/3 3, Phase 2 37, Phase 1/2 9, Phase 1 22) 2020: 667 trials (Observational 226, Not applicable 345, Phase 4 15, Phase 3 24, Phase 2/3 5, Phase 2 20, Phase 1/2 11, Phase 1 21) 2021: 888 trials (Other 1, Observational 312, Not applicable 444, Phase 4 22, Phase 3 35, Phase 2/3 9, Phase 2 40, Phase 1/2 9, Phase 1 16) 2022: 855 trials (Observational 260, Not applicable 466, Phase 4 28, Phase 3 37, Phase 2/3 3, Phase 2 40, Phase 1/2 8, Phase 1 13) 2023: 975 trials (Observational 295, Not applicable 527, Phase 4 29, Phase 3 38, Phase 2/3 12, Phase 2 44, Phase 1/2 8, Phase 1 22) 2024: 1,010 trials (Observational 268, Not applicable 588, Phase 4 30, Phase 3 40, Phase 2/3 14, Phase 2 36, Phase 1/2 6, Phase 1 28) 2025: 1,028 trials (Observational 242, Not applicable 600, Phase 4 30, Phase 3 57, Phase 2/3 10, Phase 2 56, Phase 1/2 11, Phase 1 22)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 873
2025 1,028
2024 1,010
2023 975
2022 855
2021 888
2020 667
2019 706
2018 668
2017 577

Forecast of the full-year count, planned starts included, not rows of this table: about 1,100 trials starting in 2026 and about 1,000 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,383 trials still running at the 2026-10-09 snapshot; registered median of 24 months across 6,714 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Cerebrovascular Disorders trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 415
Phase 1/2 215
Phase 2 778
Phase 2/3 164
Phase 3 729
Phase 4 538
Not applicable 6,099
Observational 3,815
Expanded access 13
Unknown 2

How many Cerebrovascular Disorders trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 795
Recruiting 2,008
Enrolling by invitation 125
Active, not recruiting 401
Available 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Cerebrovascular Disorders trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
VA Office of Research and Development 95
National Institute of Neurological Disorders and Stroke (NINDS) 80
National Heart, Lung, and Blood Institute (NHLBI) 61

Which drugs are being tested for Cerebrovascular Disorders? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Tenecteplase 69
Rivaroxaban 66
ATORVASTATIN 41
Cilostazol 40

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
EC Aspirin 136
Clopidogrel 75 72
Alteplase t-PA 67
Conventional Therapy 54
Control (placebo) group 53

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Cerebrovascular Disorders trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Other 16,347 16
MVE 6,060 1
Surgical and medical procedures 5,459 3
Pneumonia 3,970 174
Cardiac disorders 3,936 7

Which publications cover Cerebrovascular Disorders? (1,241)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (18)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages