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Condition (MeSH)

Ductus Arteriosus, Patent

ClinicalTrials.gov lists 137 trials for Ductus Arteriosus, Patent or a narrower condition beneath it. Abbott Medical Devices has the most among industry and government lead sponsors, with 4.

MeSH D004374 Cardiovascular Diseases C14 C16 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 15 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 10 Phase 4 Phase 4 8 Not applicable Not applicable 35 Observational Observational 55 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 15 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 10 Phase 4 Phase 4 8 Not applicable Not applicable 35 Observational Observational 55

Trials per phase (log scale)

137 of the 137 trials are tagged with Ductus Arteriosus, Patent itself; the rest are tagged with a narrower condition beneath it.

Get the Ductus Arteriosus, Patent report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Ductus Arteriosus, Patent trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 10

1993: 1 trials (Phase 3 1) 1998: 1 trials (Observational 1) 1999: 1 trials (Not applicable 1) 2002: 4 trials (Observational 1, Not applicable 1, Phase 3 2) 2003: 1 trials (Phase 2 1) 2004: 2 trials (Not applicable 1, Phase 4 1) 2005: 4 trials (Observational 2, Not applicable 1, Phase 4 1) 2007: 5 trials (Observational 1, Not applicable 2, Phase 4 2) 2008: 7 trials (Observational 2, Not applicable 2, Phase 2/3 2, Phase 2 1) 2009: 7 trials (Observational 1, Not applicable 4, Phase 4 1, Phase 3 1) 2010: 3 trials (Observational 2, Phase 2 1) 2011: 7 trials (Observational 4, Not applicable 3) 2012: 4 trials (Phase 4 2, Phase 3 1, Phase 2 1) 2013: 4 trials (Observational 1, Not applicable 1, Phase 2 2) 2014: 3 trials (Observational 1, Phase 2/3 1, Phase 2 1) 2015: 9 trials (Observational 4, Not applicable 2, Phase 4 1, Phase 2 2) 2016: 8 trials (Observational 3, Not applicable 2, Phase 3 2, Phase 2 1) 2017: 9 trials (Observational 3, Not applicable 3, Phase 3 1, Phase 2/3 1, Phase 1 1) 2018: 8 trials (Observational 2, Not applicable 2, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2019: 8 trials (Observational 5, Not applicable 1, Phase 3 1, Phase 2/3 1) 2020: 10 trials (Observational 6, Not applicable 3, Phase 2/3 1) 2021: 9 trials (Observational 5, Not applicable 2, Phase 2/3 1, Phase 2 1) 2022: 2 trials (Observational 1, Phase 2 1) 2023: 6 trials (Observational 4, Not applicable 1, Phase 2 1) 2024: 7 trials (Observational 3, Not applicable 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2025: 4 trials (Observational 2, Not applicable 1, Phase 2/3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 4
2024 7
2023 6
2022 2
2021 9
2020 10
2019 8
2018 8
2017 9
2016 8

No forecast is made for this condition: it averages 4.2 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Ductus Arteriosus, Patent trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 2
Phase 2 15
Phase 2/3 9
Phase 3 10
Phase 4 8
Not applicable 35
Observational 55

How many Ductus Arteriosus, Patent trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 9
Active, not recruiting 6
Completed 69
Suspended 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Ductus Arteriosus, Patent trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Abbott Medical Devices 4
Lifetech Scientific (Shenzhen) Co., Ltd. 3

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
A3: Acetaminophen (Tylenol caplets®, from Janssen-Cilag, S.A. de C.V.) 23
Ibuprofen 2% 22
Indomethacin SR 13
Oral Ibuprofen 6
NaCl 0.9% NS 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Ductus Arteriosus, Patent trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Necrotising enterocolitis neonatal 36 1
necrotizing enterocolitis 36 1
ROP Stage II-IV 17 1
Death 10 3
Sepsis neonatal 10 1

Which publications cover Ductus Arteriosus, Patent? (284)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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