Condition (MeSH)
Dysmenorrhea
ClinicalTrials.gov lists 320 trials for Dysmenorrhea or a narrower condition beneath it. Bayer has the most among industry and government lead sponsors, with 10.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
320 of the 320 trials are tagged with Dysmenorrhea itself; the rest are tagged with a narrower condition beneath it.
When did Dysmenorrhea trials start? (27)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 44
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 30 |
| 2025 | 40 |
| 2024 | 44 |
| 2023 | 22 |
| 2022 | 24 |
| 2021 | 12 |
| 2020 | 9 |
| 2019 | 14 |
| 2018 | 14 |
| 2017 | 18 |
Showing 10 of 27 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 37 trials starting in 2026 and about 35 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 25 months from start to primary completion across 19 trials still running at the 2026-10-09 snapshot; registered median of 10 months across 197 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Dysmenorrhea trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 11 |
| Phase 1/2 | 2 |
| Phase 2 | 24 |
| Phase 2/3 | 4 |
| Phase 3 | 35 |
| Phase 4 | 20 |
| Not applicable | 176 |
| Observational | 48 |
How many Dysmenorrhea trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 22 |
| Recruiting | 40 |
| Enrolling by invitation | 4 |
| Active, not recruiting | 8 |
| Completed | 185 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Dysmenorrhea trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bayer | 10 |
| AbbVie | 7 |
| Nobelpharma | 6 |
| Abbott | 4 |
| Kissei Pharmaceutical Co., Ltd. | 4 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Dysmenorrhea? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Elagolix | 8 |
| Linzagolix | 4 |
| Asoprisnil | 3 |
| Relugolix | 3 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Ibuprofen 2% | 6 |
| 1: Naproxen | 5 |
| A3: Acetaminophen (Tylenol caplets®, from Janssen-Cilag, S.A. de C.V.) | 5 |
| Estradiol /norethindrone acetate (E2/NETA) | 5 |
| Add-back capsule (E2 1 mg / NETA 0.5 mg) | 4 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Dysmenorrhea trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| ENDOMETRIOSIS | 10 | 3 |
| ABDOMINAL PAIN | 9 | 2 |
| ABORTION INDUCED | 9 | 4 |
| PELVIC PAIN | 9 | 4 |
| ABORTION SPONTANEOUS | 6 | 4 |
Showing 5 of 10 adverse events.
Which publications cover Dysmenorrhea? (404)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| The effect of acupressure on pain, menstrual symptoms, and comfort in adolescents with primary dysmenorrhea: a single-blind randomized controlled trial. | BMC complementary medicine and therapies | 2025 | Yes |
| A pilot longitudinal study of decrease in cognitive functions during the most painful day of the period among women with primary dysmenorrhea. | Archives of gynecology and obstetrics | 2025 | Yes |
| The Effects of Acupressure and Massage on Pain, Menstrual Symptoms, and Quality of Life in Primary Dysmenorrhea: A Randomized Controlled Trial. | Journal of integrative and complementary medicine | 2025 | Yes |
| The prevalence and associated risk factors of primary dysmenorrhea among women in Beijing: a cross-sectional study. | Scientific reports | 2025 | Yes |
| Working ability, Location, Intensity, Days of Pain, Dysmenorrhea (WaLIDD): cross-cultural adaptation, reliability, and validity of the Turkish version. | BMC women's health | 2025 | Yes |
Showing 5 of 404 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.