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Condition (MeSH)

Eclampsia

ClinicalTrials.gov lists 74 trials for Eclampsia or a narrower condition beneath it. NICHD Global Network for Women's and Children's Health has the most among industry and government lead sponsors, with 2.

MeSH D004461 Urogenital Diseases C12
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Phase 1 Phase 1 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 7 Not applicable Not applicable 27 Observational Observational 34 Phase 1 Phase 1 1 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 7 Not applicable Not applicable 27 Observational Observational 34

Trials per phase (log scale)

74 of the 74 trials are tagged with Eclampsia itself; the rest are tagged with a narrower condition beneath it.

Get the Eclampsia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Eclampsia trials start? (22)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 7

1990: 1 trials (Observational 1) 1991: 1 trials (Phase 3 1) 2003: 1 trials (Phase 3 1) 2004: 1 trials (Observational 1) 2008: 3 trials (Observational 2, Not applicable 1) 2009: 1 trials (Phase 4 1) 2010: 1 trials (Observational 1) 2012: 5 trials (Observational 2, Not applicable 2, Phase 2 1) 2013: 7 trials (Observational 4, Not applicable 3) 2014: 2 trials (Observational 1, Not applicable 1) 2015: 5 trials (Observational 2, Not applicable 2, Phase 2/3 1) 2016: 6 trials (Observational 3, Not applicable 1, Phase 4 2) 2017: 6 trials (Observational 4, Not applicable 2) 2018: 2 trials (Observational 1, Not applicable 1) 2019: 4 trials (Observational 2, Not applicable 2) 2020: 1 trials (Observational 1) 2021: 3 trials (Observational 1, Not applicable 1, Phase 1 1) 2022: 3 trials (Observational 1, Not applicable 2) 2023: 7 trials (Observational 2, Not applicable 4, Phase 4 1) 2024: 5 trials (Observational 3, Not applicable 1, Phase 4 1) 2025: 2 trials (Observational 1, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 7
2025 2
2024 5
2023 7
2022 3
2021 3
2020 1
2019 4
2018 2
2017 6

No forecast is made for this condition: it averages 4.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 34 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 18 months across 45 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Eclampsia trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 2 1
Phase 2/3 1
Phase 3 3
Phase 4 7
Not applicable 27
Observational 34

How many Eclampsia trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 6
Active, not recruiting 3
Completed 42
Terminated 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Eclampsia trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
NICHD Global Network for Women's and Children's Health 2
Africa Clinical Research Network (ACRN) 1

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Labetolol 2
EC Aspirin 1
Bloodwork, baseline 1
Ibuprofen 2% 1
Infusion 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Eclampsia trials report? (2)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Inpatient readmission 3 1
Acute postpartum elevation of liver function tests 1 1

Which publications cover Eclampsia? (89)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia. The Cochrane database of systematic reviews 2023 Yes
Extended Perinatal Mortality Audit in a Rural Hospital in India. American journal of perinatology 2023 Yes
Duration of postpartum magnesium sulfate for seizure prophylaxis in women with preeclampsia: a systematic review and meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 Yes
Preeclampsia and eclampsia: the conceptual evolution of a syndrome. American journal of obstetrics and gynecology 2022 Yes
Trends in Hypertensive Disorders of Pregnancy in the United States From 1989 to 2020. Obstetrics and gynecology 2022 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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