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Condition (MeSH)

Emergencies

ClinicalTrials.gov lists 1,310 trials for Emergencies or a narrower condition beneath it.

MeSH D004630 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 27 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 41 Phase 4 Phase 4 104 Not applicable Not applicable 591 Observational Observational 524 Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 27 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 41 Phase 4 Phase 4 104 Not applicable Not applicable 591 Observational Observational 524

Trials per phase (log scale)

1,310 of the 1,310 trials are tagged with Emergencies itself; the rest are tagged with a narrower condition beneath it.

Get the Emergencies report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Emergencies trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 6 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 97

1998: 1 trials (Phase 3 1) 2000: 1 trials (Observational 1) 2001: 1 trials (Not applicable 1) 2002: 1 trials (Not applicable 1) 2003: 4 trials (Not applicable 2, Phase 3 1, Phase 2/3 1) 2004: 8 trials (Observational 3, Not applicable 2, Phase 3 2, Phase 2 1) 2005: 14 trials (Observational 6, Not applicable 2, Phase 4 1, Phase 3 3, Phase 2/3 1, Phase 1/2 1) 2006: 12 trials (Not applicable 8, Phase 4 2, Phase 3 1, Phase 2 1) 2007: 29 trials (Observational 4, Not applicable 11, Phase 4 10, Phase 3 2, Phase 2 2) 2008: 19 trials (Observational 8, Not applicable 6, Phase 4 4, Phase 1/2 1) 2009: 20 trials (Observational 9, Not applicable 7, Phase 4 3, Phase 2 1) 2010: 41 trials (Observational 11, Not applicable 18, Phase 4 4, Phase 3 5, Phase 2 1, Phase 1/2 1, Phase 1 1) 2011: 31 trials (Observational 10, Not applicable 12, Phase 4 4, Phase 3 3, Phase 2 2) 2012: 39 trials (Observational 11, Not applicable 18, Phase 4 7, Phase 3 1, Phase 2 1, Phase 1 1) 2013: 42 trials (Observational 17, Not applicable 20, Phase 4 3, Phase 2 1, Phase 1 1) 2014: 44 trials (Observational 22, Not applicable 15, Phase 4 6, Phase 3 1) 2015: 61 trials (Observational 24, Not applicable 23, Phase 4 11, Phase 3 1, Phase 2 2) 2016: 61 trials (Observational 24, Not applicable 31, Phase 4 4, Phase 2/3 1, Phase 1 1) 2017: 68 trials (Observational 30, Not applicable 26, Phase 4 5, Phase 3 2, Phase 2/3 1, Phase 2 3, Phase 1 1) 2018: 81 trials (Observational 41, Not applicable 32, Phase 4 4, Phase 3 3, Phase 2 1) 2019: 88 trials (Observational 34, Not applicable 44, Phase 4 9, Phase 2 1) 2020: 91 trials (Observational 52, Not applicable 28, Phase 4 9, Phase 2 2) 2021: 96 trials (Observational 39, Not applicable 50, Phase 4 3, Phase 3 2, Phase 2 1, Phase 1 1) 2022: 87 trials (Observational 47, Not applicable 31, Phase 4 4, Phase 3 2, Phase 2 1, Phase 1 2) 2023: 81 trials (Observational 35, Not applicable 36, Phase 4 4, Phase 3 2, Phase 2/3 2, Phase 2 1, Phase 1 1) 2024: 93 trials (Observational 24, Not applicable 59, Phase 4 1, Phase 3 4, Phase 2 3, Phase 1/2 1, Phase 1 1) 2025: 97 trials (Observational 37, Not applicable 52, Phase 4 4, Phase 3 1, Phase 2 2, Phase 1/2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 91
2025 97
2024 93
2023 81
2022 87
2021 96
2020 91
2019 88
2018 81
2017 68

Forecast of the full-year count, planned starts included, not rows of this table: about 110 trials starting in 2026 and about 100 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 103 trials still running at the 2026-10-09 snapshot; registered median of 13 months across 864 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Emergencies trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 12
Phase 1/2 5
Phase 2 27
Phase 2/3 6
Phase 3 41
Phase 4 104
Not applicable 591
Observational 524

How many Emergencies trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 72
Recruiting 140
Enrolling by invitation 12
Active, not recruiting 30
Completed 784

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Emergencies? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PMI-150 (intranasal ketamine) 15
arveles 7
FENTANYL 5
PROPOFOL 5

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
A3: Acetaminophen (Tylenol caplets®, from Janssen-Cilag, S.A. de C.V.) 18
PO Morphine 16
Hydromorphone ER 13
D. Midazolam 9
Dexamethasone/Dexamethasone acetate 7

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Emergencies trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Throat/mouth irritation (extreme) 50 1
Inadvertent extubation, device removal, awareness with paralysis 19 1
Cardiac Disorders 18 1
Readmission for chest pain. 17 1
Gastrointestinal Disorders 14 1

Which publications cover Emergencies? (758)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages