Condition (MeSH)
Esophageal Atresia
ClinicalTrials.gov lists 37 trials for Esophageal Atresia or a narrower condition beneath it. Cook Research Incorporated has the most among industry and government lead sponsors, with 1.
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Trials per phase
37 of the 37 trials are tagged with Esophageal Atresia itself; the rest are tagged with a narrower condition beneath it.
When did Esophageal Atresia trials start? (15)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 2 |
| 2024 | 5 |
| 2023 | 3 |
| 2022 | 1 |
| 2021 | 4 |
| 2020 | 5 |
| 2019 | 3 |
| 2018 | 4 |
| 2017 | 4 |
| 2014 | 1 |
Showing 10 of 15 earlier years.
No forecast is made for this condition: it averages 2.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Esophageal Atresia trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
| Not applicable | 16 |
| Observational | 19 |
How many Esophageal Atresia trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 7 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 16 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Esophageal Atresia trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Cook Research Incorporated | 1 |
Which drugs are being tested for Esophageal Atresia? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| INTRALIPID | 1 |
| Omeprazole 20 mg | 1 |
| DEXMEDETOMIDINE | 1 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| data collection | 1 |
| Antacids | 1 |
| Oral Glucose | 1 |
| OMEGAVEN 10%® | 1 |
| Budesonide EC | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Esophageal Atresia? (87)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Retrospective case-control study of nutritional and respiratory status in children with type III esophageal atresia. | Journal of pediatric gastroenterology and nutrition | 2026 | Yes |
| Long-term outcome of oesophageal atresia in adolescence (TransEAsome): a national French cohort study protocol. | BMJ open | 2025 | Yes |
| Update on aortopexy and posterior tracheopexy for tracheomalacia in patients with esophageal atresia. | Surgery today | 2024 | Yes |
| Comparison of robotic versus thoracoscopic repair for congenital esophageal atresia: a propensity score matching analysis. | International journal of surgery (London, England) | 2024 | Yes |
| Does primary posterior tracheopexy prevent collapse of the trachea in newborns with oesophageal atresia and tracheomalacia? A study protocol for an international, multicentre randomised controlled trial (PORTRAIT trial). | BMJ open | 2024 | Yes |
Showing 5 of 87 publications.
Prevalence (42)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Esophageal atresia | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Exact |
| Esophageal atresia | Prevalence at birth | 1-5 / 10 000 | United Kingdom | GB | Exact |
| Esophageal atresia | Prevalence at birth | 1-5 / 10 000 | United States | US | Exact |
| Esophageal atresia | Prevalence at birth | 1-5 / 10 000 | United States | US | Exact |
| Esophageal atresia | Prevalence at birth | 1-5 / 10 000 | Ireland | Not stated | Exact |
Showing 5 of 42 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Esophageal atresia | 1199 | Exact | Orphadata Science knowledge files, Product 1 |
| Esophageal atresia | 1199 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.