Condition (MeSH)
Esophageal Stenosis
ClinicalTrials.gov lists 45 trials for Esophageal Stenosis or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
45 of the 45 trials are tagged with Esophageal Stenosis itself; the rest are tagged with a narrower condition beneath it.
When did Esophageal Stenosis trials start? (17)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 3 |
| 2024 | 1 |
| 2023 | 2 |
| 2022 | 3 |
| 2021 | 2 |
| 2020 | 7 |
| 2019 | 6 |
| 2017 | 1 |
| 2016 | 2 |
Showing 10 of 17 earlier years.
No forecast is made for this condition: it averages 2.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Esophageal Stenosis trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 6 |
| Phase 3 | 1 |
| Phase 4 | 5 |
| Not applicable | 24 |
| Observational | 7 |
How many Esophageal Stenosis trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 5 |
| Completed | 15 |
| Terminated | 6 |
| Withdrawn | 4 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Esophageal Stenosis trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Cook Group Incorporated | 2 |
| GIE Medical | 2 |
Which drugs are being tested for Esophageal Stenosis? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PREDNISOLONE | 3 |
| Tranilast | 1 |
| Prednisone | 1 |
| METHYLPREDNISOLONE | 1 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Mitomycin C 0.02% | 3 |
| oral steroid administration（prednisone） | 1 |
| Budesonide intervention | 1 |
| Collagenase histiolyticum | 1 |
| CRYOTHERAPY | 1 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Esophageal Stenosis trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Severe pain | 18 | 1 |
| pneumonia | 13 | 1 |
| Device dislocation | 10 | 1 |
| Hemorrhage | 9 | 1 |
| Chest pain | 7 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Esophageal Stenosis? (142)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Endoscopic suturing to prevent migration of esophageal fully covered self-expandable metal stents: a randomized controlled trial (with video). | Gastrointestinal endoscopy | 2025 | Yes |
| The occurrence and development mechanisms of esophageal stricture: state of the art review. | Journal of translational medicine | 2024 | Yes |
| Administration of oral prednisolone to prevent esophageal stricture after balloon-type radiofrequency ablation for ultralong-segment esophageal neoplasia. | Gastrointestinal endoscopy | 2024 | Yes |
| Esophageal Self-Dilation in Benign Refractory Esophageal Strictures: Outcomes from a Randomized Controlled Trial and a Prospective Observational Study. | Digestive diseases and sciences | 2024 | Yes |
| Risk factors for and treatment of anastomotic strictures after Ivor Lewis esophagectomy. | Surgical endoscopy | 2024 | Yes |
Showing 5 of 142 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.