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Condition (MeSH)

Hepatomegaly

ClinicalTrials.gov lists 12 trials for Hepatomegaly or a narrower condition beneath it. CENTOGENE GmbH Rostock has the most among industry and government lead sponsors, with 3.

MeSH D006529 Digestive System Diseases C06 C23
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Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 3 Not applicable Not applicable 1 Observational Observational 4 Expanded access Expanded access 1 Phase 2 Phase 2 3 Phase 2/3 Phase 2/3 3 Not applicable Not applicable 1 Observational Observational 4 Expanded access Expanded access 1

Trials per phase

12 of the 12 trials are tagged with Hepatomegaly itself; the rest are tagged with a narrower condition beneath it.

Get the Hepatomegaly report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hepatomegaly trials start? (6)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 2/3
  • Not applicable
  • Observational

Top of scale: 4

2007: 2 trials (Phase 2/3 2) 2008: 1 trials (Phase 2/3 1) 2015: 1 trials (Phase 2 1) 2018: 4 trials (Observational 3, Phase 2 1) 2019: 2 trials (Observational 1, Phase 2 1) 2025: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 1
2019 2
2018 4
2015 1
2008 1
2007 2

No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hepatomegaly trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 3
Phase 2/3 3
Not applicable 1
Observational 4
Expanded access 1

How many Hepatomegaly trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 1
Active, not recruiting 1
Completed 3
Terminated 1
Withdrawn 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hepatomegaly trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
CENTOGENE GmbH Rostock 3
Pfizer 1
SWOG Cancer Research Network 1

Which drugs are being tested for Hepatomegaly? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
NIVOLUMAB 1
Ursodeoxycholic Acid 1
S-Adenosyl-L-Methionine 1

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
LAR Lanreotide 2
Ruxolitinib IR 1
LAR Octreotide 1
Plant cell expressed recombinant glucocerebrosidase (prGCD) 1
Isatuximab SC 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hepatomegaly trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Fever 3 2
Hypokalemia 3 1
Lung infection 3 1
Abdominal pain 2 1
Anemia 2 1

Which publications cover Hepatomegaly? (47)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Secondary systemic amyloidosis diagnosed by endoscopic ultrasound-guided liver biopsy. Journal of gastrointestinal and liver diseases : JGLD 2018 Yes
First-year medical students use of ultrasound or physical examination to diagnose hepatomegaly and ascites: a randomized controlled trial. Journal of ultrasound 2017 Yes
Liver involvement in early autosomal-dominant polycystic kidney disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2015 Yes
Lanreotide Reduces Liver Volume, But Might Not Improve Muscle Wasting or Weight Loss, in Patients With Symptomatic Polycystic Liver Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2015 Yes
Intrahepatic left to right portoportal venous collateral vascular formation in patients undergoing right portal vein ligation. Cardiovascular and interventional radiology 2013 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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