Condition (MeSH)
Hernia, Hiatal
ClinicalTrials.gov lists 83 trials for Hernia, Hiatal or a narrower condition beneath it. EndoGastric Solutions has the most among industry and government lead sponsors, with 3.
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Trials per phase (log scale)
83 of the 83 trials are tagged with Hernia, Hiatal itself; the rest are tagged with a narrower condition beneath it.
When did Hernia, Hiatal trials start? (25)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 11
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 7 |
| 2024 | 9 |
| 2023 | 11 |
| 2022 | 2 |
| 2021 | 7 |
| 2020 | 4 |
| 2019 | 3 |
| 2018 | 1 |
| 2016 | 7 |
Showing 10 of 25 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 3 trials starting in 2026 and about 5 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 4 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.
Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 36 months across 44 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Hernia, Hiatal trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2/3 | 1 |
| Phase 3 | 2 |
| Phase 4 | 5 |
| Not applicable | 48 |
| Observational | 27 |
How many Hernia, Hiatal trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 8 |
| Recruiting | 14 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 5 |
| Completed | 39 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Hernia, Hiatal trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| EndoGastric Solutions | 3 |
| M.S.T. Medical Surgery Technology LTD. | 2 |
| Zagazig University | 2 |
Which drugs are being tested for Hernia, Hiatal? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| +/- Bupivacaine HCl | 1 |
Interventions as named in the registry (3)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Rectointercostal facial plane block using bupivacaine 0.25% | 1 |
| Blood collection | 1 |
| L:Lidocaine | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Hernia, Hiatal trials report? (9)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Acute respiratory distress | 1 | 1 |
| Chest Pain | 1 | 1 |
| Emergency room admission > 24 hours due to heart failure | 1 | 1 |
| Hospital admission > 24 hours due to strep toxic shock syndrome | 1 | 1 |
| Musculoskeletal pain | 1 | 1 |
Showing 5 of 9 adverse events.
Which publications cover Hernia, Hiatal? (133)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Anterior Gastropexy for Paraesophageal Hernia Repair: A Randomized Clinical Trial. | JAMA surgery | 2025 | Yes |
| Hiatal Hernia Repair With Tension-Free Mesh or Crural Sutures Alone in Antireflux Surgery: A 13-Year Follow-Up of a Randomized Clinical Trial. | JAMA surgery | 2024 | Yes |
| Clinical and computed tomography outcomes after mesh-enforced hiatoplasty and anterior hemi-fundoplication in large hiatal hernia repair. | World journal of surgery | 2024 | Yes |
| Improving the Diagnostic Yield of High-Resolution Esophageal Manometry for GERD: The "Straight Leg-Raise" International Study. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association | 2023 | Yes |
| Surgical treatment of large and complicated hiatal hernias with the new resorbable mesh with hydrogel barrier (Phasix™ ST): a preliminary study. | Journal of robotic surgery | 2023 | Yes |
Showing 5 of 133 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.