Condition (MeSH)
Hydrocephalus, Normal Pressure
ClinicalTrials.gov lists 63 trials for Hydrocephalus, Normal Pressure or a narrower condition beneath it. CereVasc Inc has the most among industry and government lead sponsors, with 3.
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Trials per phase (log scale)
63 of the 63 trials are tagged with Hydrocephalus, Normal Pressure itself; the rest are tagged with a narrower condition beneath it.
When did Hydrocephalus, Normal Pressure trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 3 |
| 2024 | 2 |
| 2023 | 4 |
| 2022 | 7 |
| 2021 | 3 |
| 2020 | 4 |
| 2019 | 7 |
| 2018 | 3 |
| 2017 | 3 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 3.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 38 months across 34 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Hydrocephalus, Normal Pressure trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 3 |
| Phase 4 | 2 |
| Not applicable | 26 |
| Observational | 29 |
How many Hydrocephalus, Normal Pressure trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 11 |
| Active, not recruiting | 4 |
| Completed | 23 |
| Terminated | 8 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Hydrocephalus, Normal Pressure trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| CereVasc Inc | 3 |
| Codman & Shurtleff | 2 |
| GE Healthcare | 2 |
| Integra LifeSciences Corporation | 2 |
| NeuroDx Development | 2 |
Interventions as named in the registry (6)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Lumbar puncture | 2 |
| Acetazolamide Pill | 2 |
| 18F-Flutemetamol | 2 |
| Control (placebo) group | 1 |
| witness CSF extraction | 1 |
Showing 5 of 6 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Hydrocephalus, Normal Pressure? (248)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| A Paradigm Shift in Hydrocephalus Management: The Promise of Endovascular Cerebrospinal Fluid Diversion. | Cardiology in review | 2025 | Yes |
| A Randomized Double-Blinded Clinical Study of Early Volumetric Changes After Shunt Surgery and MRI-Resistance of the Codman Certas® Plus Shunt Valve. | World neurosurgery | 2025 | Yes |
| Gait characteristics in idiopathic normal pressure hydrocephalus: A controlled study using an inertial sensor system. | PloS one | 2025 | Yes |
| A Randomized Trial of Shunting for Idiopathic Normal-Pressure Hydrocephalus. | The New England journal of medicine | 2025 | Yes |
| Noninvasive assessment of glymphatic dysfunction in idiopathic normal pressure hydrocephalus with diffusion tensor imaging. | Journal of neurosurgery | 2024 | Yes |
Showing 5 of 248 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.