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Condition (MeSH)

Hyperaldosteronism

ClinicalTrials.gov lists 194 trials for Hyperaldosteronism or a narrower condition beneath it.

MeSH D006929 Endocrine System Diseases C19
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Phase 1 Phase 1 2 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 13 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 4 Phase 4 Phase 4 16 Not applicable Not applicable 53 Observational Observational 103 Phase 1 Phase 1 2 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 13 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 4 Phase 4 Phase 4 16 Not applicable Not applicable 53 Observational Observational 103

Trials per phase (log scale)

190 of the 194 trials are tagged with Hyperaldosteronism itself; the rest are tagged with a narrower condition beneath it.

Get the Hyperaldosteronism report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hyperaldosteronism trials start? (25)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 24

1998: 1 trials (Observational 1) 1999: 1 trials (Observational 1) 2002: 2 trials (Observational 1, Phase 4 1) 2005: 2 trials (Observational 2) 2006: 1 trials (Phase 4 1) 2007: 4 trials (Observational 2, Phase 4 2) 2008: 2 trials (Observational 1, Phase 2 1) 2009: 3 trials (Observational 1, Not applicable 2) 2010: 2 trials (Observational 1, Phase 3 1) 2011: 3 trials (Observational 2, Phase 4 1) 2012: 3 trials (Observational 1, Not applicable 2) 2013: 8 trials (Observational 3, Not applicable 3, Phase 2 2) 2014: 4 trials (Observational 4) 2015: 2 trials (Observational 2) 2016: 10 trials (Observational 7, Not applicable 3) 2017: 11 trials (Observational 8, Not applicable 1, Phase 3 1, Phase 2 1) 2018: 12 trials (Observational 6, Not applicable 4, Phase 3 1, Phase 1 1) 2019: 8 trials (Observational 3, Not applicable 2, Phase 2/3 1, Phase 2 1, Phase 1 1) 2020: 8 trials (Observational 4, Not applicable 3, Phase 2 1) 2021: 11 trials (Observational 8, Not applicable 2, Phase 2 1) 2022: 16 trials (Observational 8, Not applicable 6, Phase 4 2) 2023: 24 trials (Observational 14, Not applicable 4, Phase 4 4, Phase 2 1, Phase 1/2 1) 2024: 22 trials (Observational 8, Not applicable 8, Phase 4 3, Phase 2 2, Phase 1/2 1) 2025: 15 trials (Observational 11, Not applicable 3, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 18
2025 15
2024 22
2023 24
2022 16
2021 11
2020 8
2019 8
2018 12
2017 11

Forecast of the full-year count, planned starts included, not rows of this table: about 21 trials starting in 2026 and about 17 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 23 trials still running at the 2026-10-09 snapshot; registered median of 29 months across 73 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hyperaldosteronism trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 1/2 2
Phase 2 13
Phase 2/3 1
Phase 3 4
Phase 4 16
Not applicable 53
Observational 103

How many Hyperaldosteronism trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 15
Recruiting 54
Enrolling by invitation 4
Active, not recruiting 7
Completed 69

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Hyperaldosteronism? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
.spironolactone 9
Finerenone 6
Baxdrostat 2

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Eplereone 5
Amlodipine 4
Dexamethasone/Dexamethasone acetate 3
HCTZ-hydrochlorothiazide 2
Mineralocorticoid Receptor Antagonists 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hyperaldosteronism trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Syncope 7 1
Haematuria 4 1
Pyrexia 4 1
Spinal Cord Compression 4 1
Back Pain 3 1

Which publications cover Hyperaldosteronism? (297)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.

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