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Condition (MeSH)

Hyperparathyroidism

ClinicalTrials.gov lists 413 trials for Hyperparathyroidism or a narrower condition beneath it. Amgen has the most among industry and government lead sponsors, with 43.

MeSH D006961 Endocrine System Diseases C19
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Phase 1 Phase 1 24 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 47 Phase 2/3 Phase 2/3 10 Phase 3 Phase 3 52 Phase 4 Phase 4 64 Not applicable Not applicable 79 Observational Observational 134 Phase 1 Phase 1 24 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 47 Phase 2/3 Phase 2/3 10 Phase 3 Phase 3 52 Phase 4 Phase 4 64 Not applicable Not applicable 79 Observational Observational 134

Trials per phase (log scale)

109 of the 413 trials are tagged with Hyperparathyroidism itself; the rest are tagged with a narrower condition beneath it.

Get the Hyperparathyroidism report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hyperparathyroidism trials start? (33)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 28

1993: 2 trials (Observational 1, Phase 2 1) 1994: 1 trials (Observational 1) 1995: 1 trials (Phase 2 1) 1997: 1 trials (Not applicable 1) 1998: 4 trials (Observational 2, Not applicable 1, Phase 2 1) 1999: 1 trials (Phase 2 1) 2000: 4 trials (Phase 3 1, Phase 2 3) 2001: 3 trials (Phase 4 1, Phase 3 1, Phase 2 1) 2002: 6 trials (Phase 4 3, Phase 3 2, Phase 2 1) 2003: 3 trials (Not applicable 2, Phase 2 1) 2004: 6 trials (Observational 1, Not applicable 1, Phase 4 3, Phase 3 1) 2005: 10 trials (Observational 6, Phase 4 4) 2006: 22 trials (Observational 6, Not applicable 3, Phase 4 7, Phase 3 1, Phase 2 2, Phase 1/2 1, Phase 1 2) 2007: 16 trials (Observational 4, Not applicable 4, Phase 4 4, Phase 3 1, Phase 1/2 1, Phase 1 2) 2008: 18 trials (Observational 5, Not applicable 4, Phase 4 3, Phase 2/3 1, Phase 2 3, Phase 1 2) 2009: 23 trials (Observational 4, Not applicable 5, Phase 4 6, Phase 3 3, Phase 2/3 1, Phase 2 3, Phase 1 1) 2010: 28 trials (Observational 5, Not applicable 3, Phase 4 11, Phase 3 3, Phase 2/3 3, Phase 1 3) 2011: 22 trials (Observational 8, Not applicable 3, Phase 4 2, Phase 3 5, Phase 2 3, Phase 1 1) 2012: 22 trials (Observational 6, Not applicable 4, Phase 4 5, Phase 3 2, Phase 2 4, Phase 1 1) 2013: 13 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 3 6, Phase 2 2, Phase 1/2 1, Phase 1 1) 2014: 17 trials (Observational 4, Not applicable 4, Phase 4 1, Phase 3 2, Phase 2 4, Phase 1 2) 2015: 22 trials (Observational 5, Not applicable 7, Phase 4 2, Phase 3 5, Phase 2/3 1, Phase 2 1, Phase 1 1) 2016: 15 trials (Observational 6, Not applicable 4, Phase 3 1, Phase 2/3 2, Phase 2 1, Phase 1 1) 2017: 14 trials (Observational 5, Not applicable 2, Phase 4 2, Phase 3 2, Phase 2 1, Phase 1 2) 2018: 17 trials (Observational 6, Not applicable 4, Phase 4 2, Phase 3 2, Phase 2 1, Phase 1 2) 2019: 13 trials (Observational 4, Not applicable 1, Phase 4 2, Phase 3 5, Phase 1 1) 2020: 10 trials (Observational 5, Not applicable 3, Phase 3 1, Phase 2 1) 2021: 15 trials (Observational 7, Not applicable 5, Phase 4 1, Phase 3 2) 2022: 17 trials (Observational 11, Not applicable 2, Phase 4 2, Phase 3 1, Phase 1 1) 2023: 18 trials (Observational 8, Not applicable 4, Phase 4 1, Phase 3 3, Phase 2 2) 2024: 15 trials (Observational 5, Not applicable 3, Phase 3 1, Phase 2 5, Phase 1 1) 2025: 15 trials (Observational 8, Not applicable 4, Phase 4 1, Phase 3 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 14
2025 15
2024 15
2023 18
2022 17
2021 15
2020 10
2019 13
2018 17
2017 14

Forecast of the full-year count, planned starts included, not rows of this table: about 16 trials starting in 2026 and about 16 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 17 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 275 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hyperparathyroidism trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 24
Phase 1/2 3
Phase 2 47
Phase 2/3 10
Phase 3 52
Phase 4 64
Not applicable 79
Observational 134

How many Hyperparathyroidism trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 10
Recruiting 41
Enrolling by invitation 3
Active, not recruiting 7
Completed 265

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hyperparathyroidism trials? (11)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Amgen 43
Abbott 13
AbbVie (prior sponsor, Abbott) 12
Kyowa Kirin Co., Ltd. 10
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 8

Which drugs are being tested for Hyperparathyroidism? (9)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cinacalcet 57
Etelcalcetide 18
Calcitriol 14
Calcium/Vitamin D 11
Doxercalciferol 10

Interventions as named in the registry (6)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Paricalitol 34
CHOLECALCIFEROL 7
MT1013 3
acid Zoledronic 3
Lanthanum Carbonate (Fosrenol, BAY77-1931) Granule 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hyperparathyroidism trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 483 38
Sepsis 358 23
Hyperkalaemia 298 19
Myocardial infarction 279 21
Cardiac failure congestive 246 19

Which publications cover Hyperparathyroidism? (137)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages