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Condition (MeSH)

Hyperplasia

ClinicalTrials.gov lists 59 trials for Hyperplasia or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 4.

MeSH D006965 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 5 Phase 4 Phase 4 4 Not applicable Not applicable 17 Observational Observational 20 Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 5 Phase 4 Phase 4 4 Not applicable Not applicable 17 Observational Observational 20

Trials per phase (log scale)

59 of the 59 trials are tagged with Hyperplasia itself; the rest are tagged with a narrower condition beneath it.

Get the Hyperplasia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hyperplasia trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 5

2001: 3 trials (Not applicable 1, Phase 3 1, Phase 2/3 1) 2002: 1 trials (Observational 1) 2003: 1 trials (Observational 1) 2004: 2 trials (Observational 1, Phase 1/2 1) 2005: 2 trials (Observational 2) 2006: 5 trials (Not applicable 1, Phase 4 1, Phase 3 1, Phase 2/3 2) 2007: 2 trials (Observational 1, Not applicable 1) 2008: 4 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2/3 1) 2009: 5 trials (Not applicable 2, Phase 4 1, Phase 3 1, Phase 1 1) 2010: 2 trials (Observational 1, Phase 4 1) 2011: 3 trials (Observational 2, Phase 3 1) 2012: 1 trials (Phase 2 1) 2013: 3 trials (Observational 2, Not applicable 1) 2014: 4 trials (Not applicable 3, Phase 4 1) 2015: 5 trials (Observational 2, Not applicable 1, Phase 2 1, Phase 1 1) 2016: 4 trials (Observational 3, Phase 2 1) 2017: 2 trials (Not applicable 1, Phase 1 1) 2018: 1 trials (Not applicable 1) 2019: 2 trials (Not applicable 1, Phase 1 1) 2021: 3 trials (Observational 1, Not applicable 2) 2022: 1 trials (Not applicable 1) 2023: 1 trials (Observational 1) 2024: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2024 1
2023 1
2022 1
2021 3
2019 2
2018 1
2017 2
2016 4
2015 5
2014 4

No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hyperplasia trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 4
Phase 1/2 1
Phase 2 4
Phase 2/3 4
Phase 3 5
Phase 4 4
Not applicable 17
Observational 20

How many Hyperplasia trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 2
Active, not recruiting 3
Completed 34
Terminated 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hyperplasia trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 4
Anesiva, Inc. 2
Proteocyte Diagnostics Inc. 2
S.L.A. Pharma AG 2
Angiotech Pharmaceuticals 1

Which drugs are being tested for Hyperplasia? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
edifoligide (E2F Decoy) 2
Eicosapentaenoic Acid 2

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Avmacol® 2
Embozene Microspheres 1
Spinal anaesthesia (sub-study 1) 1
PNEUMOSTEM 1
Saw Palmetto - weeks 24 - 48 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hyperplasia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 4 1
Bowel Obstruction 2 1
Elective knee replacement 2 1
Infection (other than UTI) 2 1
Small bowel obstruction 2 1

Which publications cover Hyperplasia? (405)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Micronodular thymic carcinoma with lymphoid hyperplasia: relevance of immunohistochemistry with a small panel of antibodies for diagnosis-a RYTHMIC study. Virchows Archiv : an international journal of pathology 2021 Yes
Prospective observational study of the efficacy of mixed methylene blue compound injection for treatment of vulvar non-neoplastic epithelial disorders. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2020 Yes
Randomized Phase IIB Trial of the Lignan Secoisolariciresinol Diglucoside in Premenopausal Women at Increased Risk for Development of Breast Cancer. Cancer prevention research (Philadelphia, Pa.) 2020 Yes
Bilateral Adrenal Hyperplasia as a Possible Mechanism for Hyperandrogenism in Women With Polycystic Ovary Syndrome. The Journal of clinical endocrinology and metabolism 2016 Yes
Immunoexpression of Th17-related cytokines in oral lichen planus. Applied immunohistochemistry & molecular morphology : AIMM 2015 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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